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NCT06728605: PANDA
Protective Effect of EECP Against Negative Inflammatory Response and Organ Dysfunction After Cardiovascular Surgery
NA trial testing Enhanced External Counterpulsation (EECP) in Coronary Heart Disease (CHD) in 400 participants. Not yet recruiting.
31 December 2025
Quick facts
| Lead sponsor | Nanjing Medical University |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | prevention |
| Enrollment | 400 |
| Start date | 31 December 2025 |
| Primary completion | 31 December 2025 |
| Estimated completion | 31 December 2025 |
| Sites | 1 location across China |
Drugs / interventions tested
- Enhanced External Counterpulsation (EECP)
- Sham Comparator
Conditions studied
- Coronary Heart Disease (CHD) — all drugs for Coronary Heart Disease (CHD) →
- Cardio-pulmonary Bypass — all drugs for Cardio-pulmonary Bypass →
- Congestive Heart Failure Chronic — all drugs for Congestive Heart Failure Chronic →
- Cardiogenic Shock Acute — all drugs for Cardiogenic Shock Acute →
Sponsor
Nanjing Medical University
Who can join
Adults 18 to 80, any sex, with Coronary Heart Disease (CHD) or Cardio-pulmonary Bypass. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Enhanced external counterpulsation (EECP) is a noninvasive, non-pharmacologic intervention proven to increase nitric oxide bioavailability in patients with coronary artery disease. Although EECP showed short-term effects in improving coronary flow in patients with coronary slow flow, whether such improvement is durable remains uncertain, and the relationships between such improvement and changes in multiple organ functions as well as inflammatory markers have not been elucidated. The purpose of this study will be to evaluate the potential clinical benefits of EECP on organ function and proinflammatory cytokine concentrations during post-acute sequela of cardiovascular surgery.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06728605
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06728605 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Nanjing Medical University
- Last refreshed: 11 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06728605.
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