NCT06728241: RecoVRy

Virtual Reality and Artificial Intelligence in Treatment for Patients With Psychosis

Recruiting now NA Last updated 25 March 2025

What this trial tests

NA trial testing RecoVRy in Psychosis in 150 participants. Currently enrolling.

Timeline

6 December 2024

Primary endpoint
31 December 2027

31 July 2028

Quick facts

Lead sponsor	Oslo University Hospital
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	150
Start date	6 December 2024
Primary completion	31 December 2027
Estimated completion	31 July 2028
Sites	2 locations across Norway

Drugs / interventions tested

• RecoVRy
• VR Games

Conditions studied

• Psychosis — all drugs for Psychosis →

Sponsor

Oslo University Hospital

Who can join

Adults 17 to 65, any sex, with Psychosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Virtual Reality (VR) has gained momentum in the treatment of various mental health conditions. Despite its potential and emphasis on better use of technology in healthcare strategies, VR therapy for severe mental illness remains underdeveloped and understudied. This will be the first randomized controlled trial to combine cognitive behavioral therapy-based VR with state-of-the-art Artificial Intelligence. Reduced quality of life, social withdrawal and inactivity found in psychotic disorders may be largely explained by avoidance due to severe symptoms of anxiety, present in as many as two-thirds of patients with schizophrenia. Alleviating anxiety may thus be key to help improve functional outcomes. The aim of this study is to provide novel information about VR therapy in psychosis employing the newly developed RecoVRy application. Study objectives are to examine short- and long-term effects on real-world functioning, psychiatric symptoms, and quality of life. A total of 150 participants will be recruited from five Norwegian hospitals. Participants will be randomly assigned to either receive the RecoVRy intervention (N=75) alongside treatment as usual or a control intervention (N=75) in which they engage with three distinct VR games. RecoVRy will generate new and important knowledge to improve mental health services in psychosis and hopefully improve existing practise and facilitate personalized treatment. RecoVRy will fill knowledge gaps concerning anxiety in psychosis, as this is often left untreated and consequently create societal benefits by increasing social and functional participation. Finally, knowledge from RecoVRy can easily be generalized to other patient groups and health sectors.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.