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NCT06725693

Glucagon-like Peptide-1 Receptor PET/CT in GLP-1R Related Disease

Recruiting now Last updated 11 February 2025
What this trial tests

trial testing 18F/68Ga-Exendin 4 in GLP1-R-related Disease in 500 participants. Currently enrolling.

Timeline
1 February 2019
Primary endpoint
1 November 2027
1 November 2027

Quick facts

Lead sponsorTianjin Medical University
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment500
Start date1 February 2019
Primary completion1 November 2027
Estimated completion1 November 2027
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Tianjin Medical University

Who can join

Adults 18 to 80, any sex, with GLP1-R-related Disease or Tumor. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To evaluate the potential usefulness of 68Ga/18F-Exendin 4 positron emission tomography/computed tomography (PET/CT) for the diagnosis of primary and metastatic lesions in various GLP-1R-related disease patients.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Advances in Endocrine Tumor PET Imaging Targeting CXCR4 and GLP-1.
    Mena E, Lindenberg L, Herscovitch P, Sadowski SM, et al · · 2025 · cited 3× · PMID 40447542 · DOI 10.1053/j.semnuclmed.2025.05.001
  2. Comparison of PET/CT using <sup>68</sup>Ga-NOTA-Exendin-4 with <sup>68</sup>Ga-DOTATATE, <sup>18</sup>F-FDG, and conventional imaging in the localization of insulinomas.
    Yu H, Bao X, Gu Y, Pan M, et al · · 2025 · cited 1× · PMID 40259061 · DOI 10.1007/s00259-025-07288-x
  3. p53: from understanding its structure to advances in therapeutic targeting.
    Wang W, Liu X, Liu H, Abolhassani H, et al · · 2026 · PMID 41942427 · DOI 10.1038/s41392-025-02549-5

Verify or expand the search:

Other recruiting trials for GLP1-R-related Disease

Currently open trials in the same condition.

Other Tianjin Medical University trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

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