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NCT06725004
Oxytocin Versus Human Chorionic Gonadotropin as Trigger in Ovulation Induction
Phase 3 trial testing Oxytocin in Ovulation Induction in 60 participants. Completed in 30 June 2024.
31 December 2023
Quick facts
| Lead sponsor | Shakeela Ishrat |
|---|---|
| Phase | Phase 3 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 1 January 2023 |
| Primary completion | 31 December 2023 |
| Estimated completion | 30 June 2024 |
| Sites | 1 location across Bangladesh |
Drugs / interventions tested
- Oxytocin (OXYTOCIN) — full drug profile →
- Human Chorionic Gonadotropin — full drug profile →
Conditions studied
- Ovulation Induction — all drugs for Ovulation Induction →
- Polycystic Ovary Syndrome — all drugs for Polycystic Ovary Syndrome →
Sponsor
Shakeela Ishrat
Who can join
Adults 20 to 40, female only, with Ovulation Induction or Polycystic Ovary Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to learn if injection oxytocin can be used as trigger in ovulation induction cycles in infertile women with polycystic ovary syndrome. The main questions it aims to answer are: * Does injection oxytocin have similar ovulation rate as injection human chorionic gonadotropin (hCG) when used as trigger? * Does injection oxytocin have similar pregnancy rate as injection human chorionic gonadotropin (hCG) when used as trigger? Researchers will compare injection oxytocin to injection hCG to see if injection oxytocin is as effective as injection hCG as trigger in ovulation induction cycles in infertile women with polycystic ovary syndrome. Participants will * Take injection oxytocin or injection hCG as trigger over three subsequent ovulation induction cycles * Be checked for ovulation by follicular rupture in TVS after 36 hours or raised serum progesterone level on day 7 after trigger * Be checked for pregnancy by urine pregnancy test kit after missed period
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06725004
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Related trials
Other trials of Oxytocin
Trials testing the same drug.
- NCT07401524 — Carbetocin Uterotonic Treatment in Twin Pregnancies for Prevention of Postpartum Hemorrhage · Phase 4 · not yet recruiting
- NCT07188207 — Rectal Misoprostol for Reducing Blood Loss in Elective Cesarean Section · NA · not yet recruiting
- NCT06968481 — Sublingual Oxytocin for the Prevention of Post-partum Hemorrhage · Phase 2 · not yet recruiting
- NCT07265180 — Oxytocin-Augmented Group Psychotherapy for Patients With Schizophrenia - an Oxytocin-dose Comparison · NA · recruiting
- NCT07119398 — Oxytocin/Foley vs. Oxytocin for Induction in Patients With PPROM · Phase 4 · recruiting
Other recruiting trials for Ovulation Induction
Currently open trials in the same condition.
- NCT06934785 — LE + CC vs. LE for Ovulation Induction · NA · recruiting
Other Shakeela Ishrat trials
Trials by the same sponsor.
- NCT06564961 — Clomiphene Citrate in Infertile Men With Idiopathic Oligoasthenozoospermia · Phase 3 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06725004 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Shakeela Ishrat
- Last refreshed: 29 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06725004.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing