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NCT06720519

Molecular Panel Evaluation for Diagnosis of Infections of the Central Nervosous System

Completed Last updated 18 December 2025
What this trial tests

trial testing QIAstat-Dx®Meningitis/Encephalite Panel in Infections Nervous System in 170 participants. Completed in 31 December 2024.

Timeline
17 April 2024
Primary endpoint
17 October 2024
31 December 2024

Quick facts

Lead sponsorIRCCS Azienda Ospedaliero-Universitaria di Bologna
StatusCompleted
Study typeOBSERVATIONAL
Enrollment170
Start date17 April 2024
Primary completion17 October 2024
Estimated completion31 December 2024
Sites1 location across Italy

Drugs / interventions tested

Conditions studied

Sponsor

IRCCS Azienda Ospedaliero-Universitaria di Bologna — full company profile →

Who can join

Eligibility, any sex, with Infections Nervous System. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Infections involving the central nervous system (CNS), such as meningitis/encephalitis (ME), are serious clinical conditions associated with high morbidity and mortality rates, as well as significant long-term consequences. ME can be caused by a wide variety of pathogenic agents. Clinical symptoms may vary and it has been shown that early identification of the pathogens causing ME allows for timely and appropriate treatment, thus reducing permanent neurological damage. The multiparameter panel "QIAstat-Dx®Meningitis/Encephalitis" can detect in one hour on a sample of 15 bacterial, viral and fungal pathogens. In the diagnostic routine, Real-time PCR takes an average of 3 hours and culture examination 2 days. In addition, compared to other comparable rapid molecular systems, the "QIAstat-Dx" platform has the ability to generate a cycle-related threshold value (Ct) for the targets detected. This value may have a correlation with the viral load and thus provide in a short time not only the result of positivity, but also an indication of the amount of virus present. Other commercially available multiparameter molecular tests provide only qualitative data.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Data sources for this page

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