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NCT06716476
Impact of Vitamin D in Rheumatoid Arthritis
Phase 4 trial testing Vitamin D in Rheumatic Arthritis in 100 participants. Completed in 31 January 2024.
31 March 2023
Quick facts
| Lead sponsor | University of Pristina |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 100 |
| Start date | 1 March 2022 |
| Primary completion | 31 March 2023 |
| Estimated completion | 31 January 2024 |
| Sites | 1 location across Kosovo |
Drugs / interventions tested
- Vitamin D
Conditions studied
- Rheumatic Arthritis — all drugs for Rheumatic Arthritis →
Sponsor
University of Pristina
Who can join
Adults 30 to 65, any sex, with Rheumatic Arthritis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this prospective, randomized, parallel-group design, double-blind, and 6-month follow-up is to evaluate the impact of 4000 IU/day vitamin D on 25-hydroxyvitamin D \[25(OH)D\] levels and inflammatory mediators in people with Rheumatoid Arthritis (RA). The main questions it aims to answer are * The level of 25(OH)D and inflammatory mediators of levels of RA differs at baseline and after 6 months of Vitamin D 4000 UI * The disease activity of AR measured by visual analogue scale (VAS) and Disease Activity Score-28 (DAS-28 score) will change in baseline and after 6 months of Vitamin D 4000 UI Researchers will compare the group of participants with Vitamin D supplementation and group of participants without D Vitamin supplementation Participants in active group will: * Take Vitamin D every day for 6 months * Visit the clinic in the first months and after 6 months for medical visits and tests.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Impact of vitamin D supplementation on disease activity and pain management in rheumatoid arthritis: a randomized double-blinded controlled study.
Rexhepi M, Krasniqi B, Hoti K, Daci A, et al · · 2025 · PMID 40646666 · DOI 10.1186/s41927-025-00543-6
Verify or expand the search:
- PubMed search for NCT06716476
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT07400757 — Statin and Vitamin D Treatment in Patients With Thyroid Eye Disease · NA · not yet recruiting
- NCT07293910 — Vonoprazan vs Proton Pump Inhibitor With Vitamin D or Probiotics Based Triple Therapy for Eradication of Helicobacter Py · Phase 2 · recruiting
Other recruiting trials for Rheumatic Arthritis
Currently open trials in the same condition.
- NCT07442773 — Intervention to Support Partners and Informal Caregivers of Frail RA-patients · NA · recruiting
- NCT07089381 — Efficacy and Safety of Resveratrol in Patients With Rheumatoid Arthritis. · NA · recruiting
- NCT06965322 — Study on the Detection of Pleuropulmonary Manifestations in Rheumatoid Arthritis · recruiting
- NCT04806620 — Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research · recruiting
- NCT06778343 — Biomarkers in Inflammatory Rheumatic Diseases Diagnosis · recruiting
Other University of Pristina trials
Trials by the same sponsor.
- NCT07175090 — Evaluation of Coconut Oil Mouth Rinse on Periodontal Parameters · EARLY_PHASE1 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06716476 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Pristina
- Last refreshed: 4 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06716476.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing