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NCT06707194
Effect and Safety of Benzathine Penicillin Combined With Etanercept on Spondyloarthritis
Phase 4 trial testing Etanercept in Spondyloarthritis (SpA) in 340 participants. Currently enrolling.
1 March 2027
Quick facts
| Lead sponsor | Nanfang Hospital, Southern Medical University |
|---|---|
| Phase | Phase 4 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 340 |
| Start date | 14 June 2025 |
| Primary completion | 1 March 2027 |
| Estimated completion | 31 July 2027 |
| Sites | 6 locations across China |
Drugs / interventions tested
- Etanercept (etanercept) — full drug profile →
- Benzathine Penicillin — full drug profile →
- Placebo
Conditions studied
- Spondyloarthritis (SpA) — all drugs for Spondyloarthritis (SpA) →
- Ankylosing Spondylitis (AS) — all drugs for Ankylosing Spondylitis (AS) →
Sponsor
Nanfang Hospital, Southern Medical University
Who can join
Adults 18 to 59, any sex, with Spondyloarthritis (SpA) or Ankylosing Spondylitis (AS). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of the study is to verify the clinical feasibility of Benzathine penicillin (BPG) /Etanercept (ETN) combination regimen in patients with spondyloarthritis (SpA) and at the same time compare Benzathine penicillin /Etanercept combination regimen and Etanercept maintenance therapy in reducing disease activity, improving patients' clinical symptoms and body function scores, enhancing quality of life, improving imaging performance and safety.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06707194
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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Other recruiting trials for Spondyloarthritis (SpA)
Currently open trials in the same condition.
- NCT06988813 — Bidirectional Cohort Study of Nanfang Spondyloarthritis · recruiting
- NCT07277491 — Assessment of Nutritional Status in Rheumatic Diseases and Association to Disease Activity · recruiting
- NCT05200715 — AutoInflammatory Disease Alliance Registry (AIDA) · recruiting
Other Nanfang Hospital, Southern Medical University trials
Trials by the same sponsor.
- NCT07091994 — A Trial of Edaravone Dexborneol in Acute Ischemic Stroke With Active Malignancy · Phase 4 · not yet recruiting
- NCT06444022 — hAESCs Prevent Acute Graft-versus-host Disease After Hematopoietic Stem Cell Transplantation · Phase 1 · withdrawn
- NCT07537777 — Benmelstobart Plus Anlotinib Combined With SBRT for Patients With Hepatocellular Carcinoma Failing First-Line Targeted T · Phase 2 · not yet recruiting
- NCT07481032 — Effect of Fufang Biejiaruangan Combined With Antiviral Therapy on the Incidence of Hepatocellular Carcinoma in Patients · NA · not yet recruiting
- NCT07511894 — Beta-Blockers on the Efficacy of Neoadjuvant Immunotherapy for Gastric Cancer · Phase 2 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06707194 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Nanfang Hospital, Southern Medical University
- Last refreshed: 26 June 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06707194.
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