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NCT06705777: RSFAhCHD60T
Randomized Study of Oral Aesculus Hippocastanum and Combinations in Hemorrhoidal Disease After 60 Days of Treatment
Phase 4 trial testing Aesculus hippocastanum, and interventions in Haemorrhoidal Disease in 120 participants. Completed in 22 November 2025.
1 September 2025
Quick facts
| Lead sponsor | Fundação Educacional Serra dos Órgãos |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 120 |
| Start date | 1 September 2024 |
| Primary completion | 1 September 2025 |
| Estimated completion | 22 November 2025 |
| Sites | 1 location across Brazil |
Drugs / interventions tested
- Aesculus hippocastanum, and interventions — full drug profile →
Conditions studied
- Haemorrhoidal Disease — all drugs for Haemorrhoidal Disease →
Sponsor
Fundação Educacional Serra dos Órgãos — full company profile →
Who can join
18 and older, any sex, with Haemorrhoidal Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To demonstrate the clinical efficacy of the combination of Aesculus hippocastanum, Polygonum acre, Smilax Pepyracea, and rutin in tablets in improving local symptoms (bleeding, pain, thrombosis, perianal dermatitis, hemorrhoidal nipple prolapse) assessed using a 100mm visual scale (VAS) over 60 days among adult patients with grade 1, 2 or 3 hemorrhoidal disease.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06705777
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other Fundação Educacional Serra dos Órgãos trials
Trials by the same sponsor.
- NCT06579482 — Clinical Trial of Aesculus Hippocastanum and Associations Versus Diosmina and Hesperidina in Chronic Venous Insuficiency · Phase 4 · completed
- NCT05221892 — Evaluation of Aminobutyric Acid, Glutamic Acid, Calcium, Thiamine, Pyridoxine and Cyanocobalamin as Therapy for Vertigo · Phase 4 · completed
- NCT03755596 — Clinical Evaluation of the Use of Ginger Extract in the Management of Motion Sickness · Phase 4 · completed
- NCT03379389 — Clinical Assessment of Urinary Antiseptics Methenamine and Methylthioninium in Recurrent Cystitis · Phase 4 · completed
- NCT03471910 — Clinical Non-inferiority Study Between Diosmin 600mg & Diosmin + Hesperidin in Symptomatic Chronic Venous Insufficiency · Phase 4 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06705777 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fundação Educacional Serra dos Órgãos
- Last refreshed: 7 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06705777.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing