Last reviewed · How we verify
NCT06704035: EaGeR
Early Screening for Gestational Diabetes Mellitus in a Low Risk Population
NA trial testing Early OGTT Results Revealed in Gestational Diabetes Mellitus (GDM) in 120 participants. Not yet recruiting.
30 April 2026
Quick facts
| Lead sponsor | National University Hospital, Singapore |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | screening |
| Enrollment | 120 |
| Start date | 1 December 2024 |
| Primary completion | 30 April 2026 |
| Estimated completion | 30 November 2026 |
| Sites | 1 location across Singapore |
Drugs / interventions tested
- Early OGTT Results Revealed
Conditions studied
- Gestational Diabetes Mellitus (GDM) — all drugs for Gestational Diabetes Mellitus (GDM) →
- Glucose Intolerance During Pregnancy — all drugs for Glucose Intolerance During Pregnancy →
Sponsor
National University Hospital, Singapore
Who can join
Adults 21 to 39, female only, with Gestational Diabetes Mellitus (GDM) or Glucose Intolerance During Pregnancy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This new feasibility pilot study aims to refine the design and protocols for a larger trial that will investigate the potential benefits of early oral glucose tolerance test (OGTT) screening in a population traditionally defined as low-risk for development of gestational diabetes. The study will evaluate its potential effectiveness in reducing the risks of neonatal morbidity/mortality and obstetric complications. Additionally, a machine learning algorithm to predict gestational diabetes mellitus (GDM) risk based on routinely obtained clinical information at pregnancy booking, and minimally invasive methods, such as continuous glucose monitoring (CGM) and gingival crevicular fluid (GCF) sampling, are being explored to predict the risk of hyperglycaemia. This study aims to investigate the utility of early pregnancy screening to enable timely detection and management of early gestational diabetes development in a low-risk population, ultimately promoting better health outcomes for mothers and their babies.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06704035
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Gestational Diabetes Mellitus (GDM)
Currently open trials in the same condition.
- NCT07436195 — Imprinting in Metabolic Diseases - Identifying Epigenetic Mechanisms in Human Gestational Diabetes Through Cell-free DNA · recruiting
- NCT07176793 — Pregnancy and Postpartum Breastfeeding Support for Patients With Gestational Diabetes · recruiting
- NCT06988306 — Lifestyle Interventions to Prevent Diabetes in U.S. Home Visiting Programs · NA · recruiting
- NCT07470320 — Placental Biology in Health and Disease · recruiting
- NCT06896799 — Determining the Effect of Food Ordering on Blood Glucose In Gestational Diabetes Mellitus (DEFI-GDM) · NA · recruiting
Other National University Hospital, Singapore trials
Trials by the same sponsor.
- NCT06027983 — Chimeric Receptor T Cells With Trastuzumab in HER2+ Advanced Breast Cancer and Other Solid Tumors · Phase 1, PHASE2 · not yet recruiting
- NCT07460505 — Mandibular Advancement to Reduce Ventricular Load and Improve Quality-of-life in Heart Failure · NA · not yet recruiting
- NCT07319676 — Antigen Targeted T Cell Therapy for Relapsed/Refractory B Cell Lymphomas · Phase 1, PHASE2 · recruiting
- NCT06983769 — CPAP vs MAD for OSA in Patients With Cognitive Impairment. A Randomized Clinical Trial · NA · recruiting
- NCT07091175 — Dupilumab Therapy in Nephrotic Syndrome in Children · Phase 2 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06704035 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National University Hospital, Singapore
- Last refreshed: 25 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06704035.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing