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NCT06693154

Calprotectin Levels in Necrotizing Enterocolitis

Completed Last updated 18 November 2024
What this trial tests

trial in Necrotising Enterocolitis Neonatal in 59 participants. Completed in 1 June 2024.

Timeline
1 June 2022
Primary endpoint
1 January 2024
1 June 2024

Quick facts

Lead sponsorAnkara Yildirim Beyazıt University
StatusCompleted
Study typeOBSERVATIONAL
Enrollment59
Start date1 June 2022
Primary completion1 January 2024
Estimated completion1 June 2024
Sites1 location across Turkey (Türkiye)

Conditions studied

Sponsor

Ankara Yildirim Beyazıt University

Who can join

Adults 3 Days to 30 Days, any sex, with Necrotising Enterocolitis Neonatal. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Necrotizing enterocolitis (NEC) is a serious condition that can affect premature babies, leading to complications like intestinal damage and infection. In our study, we measured specific markers (called calprotectin) in blood and stool to understand how severe NEC is and predict outcomes. We found that these markers were higher in babies with more severe NEC (stage 3), especially in those who needed surgery or sadly did not survive. This information can help doctors detect NEC earlier, understand its severity, and make better decisions for treating affected babies.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. A comparative study of serum and fecal calprotectin levels in necrotizing enterocolitis.
    Erol S, Tayman C, Korkut S, Çakir U, et al · · 2025 · PMID 40784368 · DOI 10.1016/j.jped.2025.101428

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