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NCT06691841
Effect of Chlorhexidine Gluconate in Oral Care of Patients With Endotracheal Intubation Based on 16sRNA Technology
NA trial testing Chlorhexidine Gluconate in Intubation, Endotracheal in 76 participants. Completed in 1 March 2024.
1 May 2023
Quick facts
| Lead sponsor | Shanghai 10th People's Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 76 |
| Start date | 1 September 2022 |
| Primary completion | 1 May 2023 |
| Estimated completion | 1 March 2024 |
| Sites | 1 location across China |
Drugs / interventions tested
- Chlorhexidine Gluconate — full drug profile →
- normal saline
Conditions studied
- Intubation, Endotracheal — all drugs for Intubation, Endotracheal →
- Oral Hygiene — all drugs for Oral Hygiene →
Sponsor
Shanghai 10th People's Hospital
Who can join
65 and older, any sex, with Intubation, Endotracheal or Oral Hygiene. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Evaluation of the application effect of compound chlorhexidine gargle in oral care of patients with endotracheal intubation based on 16s RNA technology.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effect of chlorhexidine vs. saline for oral care on oral microbiota and prognosis of elderly mechanically ventilated patients in the intensive care unit: a single-center, single-blind, randomized controlled trial.
Qiu C, Tang L, Hang Z, Wei K, et al · · 2025 · PMID 41456054 · DOI 10.1186/s12903-025-07579-7
Verify or expand the search:
- PubMed search for NCT06691841
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Chlorhexidine Gluconate
Trials testing the same drug.
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- NCT05110001 — Rose Bengal Electromagnetic Activation With Green Light for Infection Reduction · Phase 3 · completed
- NCT05059145 — A Clinical Trial for Chlorhexidine as Treatment for Vulvovaginal Candidiasis · Phase 2 · unknown
Other recruiting trials for Intubation, Endotracheal
Currently open trials in the same condition.
- NCT07380763 — Comparison of Peri-intubation Oxygenation Values and Complications in Patients Intubated With the Delayed Versus Rapid S · NA · recruiting
Other Shanghai 10th People's Hospital trials
Trials by the same sponsor.
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- NCT07328100 — Efficacy and Safety of Coenzyme I for Injection on Vascular Aging. · NA · not yet recruiting
- NCT06783296 — Efficacy and Safety of Renal Denervation on Isolated Diastolic Hypertension · NA · not yet recruiting
- NCT07204496 — A Clinical Study on the Safety, Tolerance, and Preliminary Efficacy of γδ-T Cell Injection in the Treatment of Advanced · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06691841 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Shanghai 10th People's Hospital
- Last refreshed: 15 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06691841.
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