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NCT06685302
Addition of Ultrasound-guided Percutaneous Neuromodulation to Ultrasound-guided Percutaneous Electrolysis and Eccentric Exercises in Patellar Tendinopathy.
NA trial testing US-guided PNM in Patellar Tendinitis in 26 participants. Completed in 27 November 2025.
31 August 2025
Quick facts
| Lead sponsor | Universidad de Zaragoza |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 26 |
| Start date | 1 May 2025 |
| Primary completion | 31 August 2025 |
| Estimated completion | 27 November 2025 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- US-guided PNM
- US-guided PE
- EE — full drug profile →
Conditions studied
- Patellar Tendinitis — all drugs for Patellar Tendinitis →
- Patella; Tendinitis — all drugs for Patella; Tendinitis →
- Patellar Tendinopathy / Jumpers Knee — all drugs for Patellar Tendinopathy / Jumpers Knee →
Sponsor
Universidad de Zaragoza — full company profile →
Who can join
Adults 18 to 50, any sex, with Patellar Tendinitis or Patella; Tendinitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Patellar tendinopathy, or "jumper's knee," is a prevalent condition involving patellar tendon degeneration due to structural overuse, common among athletes, particularly males over 18 in sports like volleyball, basketball, or football. It causes tendon thickening, collagen disorganization, fibroblast proliferation, neovascularization, and neurogenesis. Symptoms include anterior knee pain that worsens with activity, tenderness at the proximal tendon insertion, and functional limitations. Diagnosis often utilizes ultrasound imaging. While surgical treatment is reserved for severe cases, non-surgical options prioritize physiotherapy-especially eccentric exercises and newer invasive techniques like percutaneous electrolysis and neuromodulation. However, there is still no research on the effects when combining these three treatment options.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06685302
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of US-guided PNM
Trials testing the same drug.
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Other Universidad de Zaragoza trials
Trials by the same sponsor.
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- NCT07066696 — Mindfulness and Compassion Program for the Improvement of Emotional and Behavioral Problems, Academic Performance and Sc · NA · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06685302 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universidad de Zaragoza
- Last refreshed: 4 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06685302.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing