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NCT06682676
Diagnostic Efficacy of CDA Nasal Provocation Test in Patients With IR
NA trial testing Nasal ventilation function test and cold and dry air nasal provocation test in Chronic Rhinitis in 100 participants. Not yet recruiting.
31 December 2027
Quick facts
| Lead sponsor | The First Affiliated Hospital with Nanjing Medical University |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | other |
| Enrollment | 100 |
| Start date | 7 November 2024 |
| Primary completion | 31 December 2027 |
| Estimated completion | 31 December 2032 |
Drugs / interventions tested
- Nasal ventilation function test and cold and dry air nasal provocation test
Conditions studied
- Chronic Rhinitis — all drugs for Chronic Rhinitis →
Sponsor
The First Affiliated Hospital with Nanjing Medical University
Who can join
Adults 18 to 65, any sex, with Chronic Rhinitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Chronic rhinitis is a common chronic nasal mucosal inflammatory disease. Its clinical symptoms and severity are diverse, mainly including allergic rhinitis, local allergic rhinitis, non-allergic rhinitis with hypereosinophilia syndrome and idiopathic rhinitis. All kinds of rhinitis have clinical symptoms such as nasal congestion, runny nose, sneezing, and nasal itching, but the causes are different. At present, the diagnosis of idiopathic rhinitis (IR) is based on detailed medical history and negative allergen test results, which is a diagnosis of exclusion. According to the position paper of the European Academy of Allergy and Clinical Immunology (EAACI), nasal hyperresponsiveness is an abnormal reaction of the nasal mucosa to stimuli that most people can tolerate. One of the distinguishing features of non-allergic rhinitis. cold dry air (CDA) nasal provocation test has been proved to be a good, safe and tolerable test for nasal hyperresponsiveness, with superior sensitivity and specificity. At present, there is still a lack of clear diagnostic criteria for IR. Therefore, optimizing CDA nasal provocation test, determining the diagnostic efficacy of CDA nasal provocation test with different parameters for IR, and initially constructing an IR diagnostic model can provide more comprehensive guidance for clinical diagnosis and treatment, which has important clinical significance.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
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- PubMed search for NCT06682676
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Related trials
Other recruiting trials for Chronic Rhinitis
Currently open trials in the same condition.
- NCT06999044 — Study on the Optimization of the Diagnostic Process for Chronic Rhinitis Using Nasal Allergen Provocation Test · recruiting
- NCT06370468 — The Epidemiological and Intrinsic Characteristics of Chronic Rhinitis · recruiting
Other The First Affiliated Hospital with Nanjing Medical University trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06682676 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The First Affiliated Hospital with Nanjing Medical University
- Last refreshed: 12 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06682676.
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