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NCT06677099
Electrical Impedance Tomography in Guiding Early and Precise Rehabilitation of Patients with Difficult Ventilator Weaning
NA trial testing chest physiotherapy in Difficult-to-Wean Patients in 80 participants. Not yet recruiting.
30 November 2025
Quick facts
| Lead sponsor | Capital Medical University |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 80 |
| Start date | 7 November 2024 |
| Primary completion | 30 November 2025 |
| Estimated completion | 30 December 2025 |
Drugs / interventions tested
- chest physiotherapy
- EIT-guided chest physiotherapy
Conditions studied
- Difficult-to-Wean Patients — all drugs for Difficult-to-Wean Patients →
Sponsor
Capital Medical University
Who can join
18 and older, any sex, with Difficult-to-Wean Patients. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Diaphragm dysfunction, ineffective chest wall and respiratory muscle function are frequently observed in critically ill patients with difficult weaning from mechanical ventilation(MV).It is the leading cause of retention of airway secretions and insufficient airway clearance.Thechest physiotherapy (CPT) of critically ill patients can reduce secretion retention. We designed a protocol to investigate the feasibility and efficacy of CPT guided by electrical impedance tomography (EIT) in Difficult-to-Wean patients.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Randomized clinical study of electrical impedance tomography-guided chest physiotherapy in difficult-to-wean patients: study protocol.
Wang H, Xi J, Jiang H. · · 2025 · PMID 40777077 · DOI 10.7717/peerj.19727
Verify or expand the search:
- PubMed search for NCT06677099
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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- NCT06642701 — Electrical Impedance Imaging Techniques in Guiding the Use of Chest Physiotherapy in Patients with Pneumonia · NA · completed
- NCT05488301 — Effects of Chest Physiotherapy in Hyperventilation Syndrome · completed
- NCT04094441 — Modeling of Chest Physiotherapy Using Impedance Measurements (PHYSIOMOD) · NA · completed
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06677099 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Capital Medical University
- Last refreshed: 6 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06677099.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing