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NCT06675448
In Search of Best Practices for Patients With Heart Failure and Secondary Mitral Regurgitation: An Evaluation of the Inova Heart Failure Treatment Algorithm
trial testing MitraClip in Mitral Regurgitation in 50 participants. Currently enrolling.
10 September 2029
Quick facts
| Lead sponsor | Inova Health Care Services |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 50 |
| Start date | 28 January 2021 |
| Primary completion | 10 September 2029 |
| Estimated completion | 10 September 2030 |
| Sites | 1 location across United States |
Drugs / interventions tested
- MitraClip
- Moderate MR
Conditions studied
- Mitral Regurgitation — all drugs for Mitral Regurgitation →
- Valvular Heart Disease — all drugs for Valvular Heart Disease →
- Heart Failure — all drugs for Heart Failure →
Sponsor
Inova Health Care Services — full company profile →
Who can join
Adults 18 to 99, any sex, with Mitral Regurgitation or Valvular Heart Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The overarching goal of this research proposal is to study the feasibility and clinical impact of implementing an Inova system-wide heart failure treatment algorithm for patients with symptomatic heart failure due to reduced left ventricular ejection fraction (HFreF) and secondary MR Aim is to check the effectiveness of the IHFTA in identifying patients who are most likely to benefit from percutaneous transcatheter Mitraclip repair in real world
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06675448
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of MitraClip
Trials testing the same drug.
- NCT06282042 — Early Transcatheter Mitral Valve Repair After Myocardial Infarction · NA · recruiting
- NCT05311163 — Change in LVEF Following Transcatheter Mitral Edge-To-Edge Repair · unknown
- NCT05292716 — Mitral Regurgitation Treatment in Advanced Heart Failure · NA · recruiting
- NCT04351984 — Transcatheter Mitral Valvuloplasty Pilot Study · completed
- NCT03891823 — Transcatheter Mitral Valve Repair for the Treatment of Mitral Valve Regurgitation In Heart Failure (The EVOLVE-MR Trial) · NA · terminated
Other recruiting trials for Mitral Regurgitation
Currently open trials in the same condition.
- NCT07450911 — A Clinical Study Evaluating the Replacement of the Native Mitral Valve Using the ReValve System · Phase 1 · recruiting
- NCT07366723 — The Role of cardIac magNeTic rEsonance in surGical Decision Making in Patients With Severe pRimAry miTral rEgurgitation · NA · active not recruiting
- NCT07007143 — STrategies for Antithrombotic tReatment Following Transcatheter Edge-to-Edge Repair in Patients Without an Indication fo · Phase 4 · recruiting
- NCT07108907 — Outcome Registry and Assessment of New Edge-to-Edge Repair · recruiting
- NCT06901466 — STrategies for Antithrombotic tReatment Following Transcatheter Edge-to-Edge Repair in Patients With an Indication for O · Phase 4 · recruiting
Other Inova Health Care Services trials
Trials by the same sponsor.
- NCT06564207 — Fostamatinib for Treating Acute Respiratory Distress Syndrome (ARDS) in Hospitalized Adults · Phase 2 · not yet recruiting
- NCT07167199 — Absorbable Staples Versus Conventional Skin Closure in Women Undergoing Cesarean Delivery · NA · not yet recruiting
- NCT07437339 — Volume Reduction for Open Fracture Irrigation · Phase 4 · recruiting
- NCT07485322 — Burn Pit Exposure in Veterans: A Cancer Screening Pilot Study at the Inova Saville Cancer Screening & Prevention Center · NA · not yet recruiting
- NCT07335224 — Men With Prostate Cancer: Optimizing Wellness by Enhanced Relief From Hot Flashes With Acupuncture · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06675448 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Inova Health Care Services
- Last refreshed: 3 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06675448.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing