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NCT06667193
Cold Water Exposure's Effects on Physical and Mental Health
NA trial testing Cold Water Immersion (CWI) - Cold Tub Immersion (CI) in Cold Exposure in 75 participants. Enrolling by invitation.
1 September 2025
Quick facts
| Lead sponsor | University of Northern Colorado |
|---|---|
| Phase | NA |
| Status | ENROLLING BY INVITATION |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | other |
| Enrollment | 75 |
| Start date | 10 October 2024 |
| Primary completion | 1 September 2025 |
| Estimated completion | 1 October 2025 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Cold Water Immersion (CWI) - Cold Tub Immersion (CI)
- Cold Water Immersion (CWI) - Cold Shower (CS)
Conditions studied
- Cold Exposure — all drugs for Cold Exposure →
Sponsor
University of Northern Colorado
Who can join
Adults 18 to 45, any sex, with Cold Exposure. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
An interest in cold-water immersion (CWI) to elicit diverse physiological effects has been prevalent for centuries. CWI typically consists of bodily exposure to water at temperatures ranging from 5-10º C for various durations. CWI has profound cultural significance in different areas of the world, such as in Scandinavian countries, and has emerged as a popular modality for its purported health-promoting effects. Individuals on social media have repeatedly advocated for CWI as a method to improve muscular recovery, enhance sleep, and increase immune and cognitive function. Because of this, companies that specialize in cold tub production have become popularized; however, individuals who are seeking a more cost-effective option are drawn toward cold showers for their preferred method of cold exposure. Despite the scarcity of rigorous research investigating the difference in effects of cold tub versus cold shower CWI, individuals on social media promoting CWI via a shower continue to praise its comparable benefits to that of a tub. Therefore, investigations of chronic CWI (utilizing both a cold tub and a cold shower) is vital. Thus, the purpose of the proposed study is to explore the varying effects of chronic CWI on neural and cognitive function using a cold tub and a cold shower. Further, the study aims to investigate performance measures and immune measures to create a comprehensive understanding of CWI's implications on human physiology over time. The investigators hypothesize measures relating to mental performance and health will improve after 4-weeks of CWI, and there will be no difference between tub and shower immersion groups.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06667193
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Related trials
Other trials of Cold Water Immersion (CWI) - Cold Tub Immersion (CI)
Trials testing the same drug.
- NCT06667479 — Cold Water Exposure and Immune Function Study · NA · completed
Other recruiting trials for Cold Exposure
Currently open trials in the same condition.
- NCT07489690 — Energy Dense Fueling for Cold-Weather Operations · NA · recruiting
- NCT06978777 — Effect of Caffeine on Cold-stimulated Brown Adipose Tissue Activity · NA · recruiting
- NCT06424132 — Thermogenic Silencer Regulatory Factors in Humans · NA · active not recruiting
- NCT03541096 — Winter-Swimming and Brown Adipose Tissue Activity in Middel-aged Obese Subjects (WinterBAT). · NA · active not recruiting
Other University of Northern Colorado trials
Trials by the same sponsor.
- NCT07480018 — Berberine Supplementation, Sprint Interval Training, and Immune Function Study · NA · recruiting
- NCT06829836 — Can You Breathe Your Way To Better Health? · NA · enrolling by invitation
- NCT06667479 — Cold Water Exposure and Immune Function Study · NA · completed
- NCT06364254 — Effects of CBD on 2 Mile Run Time Trial Performance · NA · active not recruiting
- NCT05850754 — 4 Week Veterans Cannabidiol Intervention · NA · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06667193 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Northern Colorado
- Last refreshed: 31 October 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06667193.
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