Last reviewed · How we verify

NCT06667167

First Line Therapy for Extensive SCLC Patients, Treated with Chemo+Keytruda Followed by Keytuda+Trodelvy

Recruiting now Phase 2 Last updated 17 January 2025
What this trial tests

Phase 2 trial testing Induction Carboplatin in NSCLC (non-small Cell Lung Cancer) in 21 participants. Currently enrolling.

Timeline
24 December 2024
Primary endpoint
1 November 2027
1 November 2028

Quick facts

Lead sponsorNir Peled
PhasePhase 2
StatusRecruiting now
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposetreatment
Enrollment21
Start date24 December 2024
Primary completion1 November 2027
Estimated completion1 November 2028
Sites1 location across Israel

Drugs / interventions tested

Conditions studied

Sponsor

Nir Peled

Who can join

Adults 18 to 99, any sex, with NSCLC (non-small Cell Lung Cancer). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Induction phase of carboplatin+etoposide+pembrolizumab followed by maintenance of Pembrolizumab+sacituzumab govitecan

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Advances in adoptive cell therapies in small cell lung cancer.
    Bragasin EI, Cheng J, Ford L, Poei D, et al · · 2025 · cited 3× · PMID 40160238 · DOI 10.37349/etat.2025.1002302
  2. Overcoming resistance to antibody-drug conjugates: from mechanistic insights to cutting-edge strategies.
    Zhou K, Liu X, Zhu H. · · 2025 · cited 2× · PMID 41185045 · DOI 10.1186/s13045-025-01752-9
  3. Redefining the Fight Against SCLC: Standards, Innovations, and New Horizons.
    Kemper M, Reitnauer LE, Lenz G, Evers G, et al · · 2025 · PMID 40647553 · DOI 10.3390/cancers17132256

Verify or expand the search:

Other Nir Peled trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06667167.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing