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NCT06667154
Efficacy Analysis of Neoadjuvant Treatment in Lung Cancer Using Low-dose Nivolumab Combined With Chemotherapy
Phase 2 trial testing Low-dose nivolumab combined with platinum-based doublet chemotherapy in Lung Cancer, Nonsmall Cell in 33 participants. Currently enrolling.
31 October 2025
Quick facts
| Lead sponsor | Aline Fusco Fares, MD |
|---|---|
| Phase | Phase 2 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 33 |
| Start date | 10 October 2023 |
| Primary completion | 31 October 2025 |
| Estimated completion | 31 October 2027 |
| Sites | 1 location across Brazil |
Drugs / interventions tested
- Low-dose nivolumab combined with platinum-based doublet chemotherapy — full drug profile →
Conditions studied
- Lung Cancer, Nonsmall Cell — all drugs for Lung Cancer, Nonsmall Cell →
- Non-Small Cell Lung Cancer NSCLC — all drugs for Non-Small Cell Lung Cancer NSCLC →
Sponsor
Aline Fusco Fares, MD — full company profile →
Who can join
18 and older, any sex, with Lung Cancer, Nonsmall Cell or Non-Small Cell Lung Cancer NSCLC. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The primary objective of this study is to assess the major pathological response (MPR) rate and pathologic complete response (pCR) rate in stage IB-IIIA non-small cell lung cancer (NSCLC) treated with a low dose of neoadjuvant immunotherapy combined with platinum doublet.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06667154
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06667154 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Aline Fusco Fares, MD
- Last refreshed: 31 October 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06667154.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing