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NCT06666946: SEPSIS-ACU
Efficacy and Safety of Electroacupuncture for ICU Sepsis Patients
NA trial testing Electroacupuncture in Sepsis in 308 participants. Currently enrolling.
1 August 2026
Quick facts
| Lead sponsor | Shusheng Li |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 308 |
| Start date | 11 February 2025 |
| Primary completion | 1 August 2026 |
| Estimated completion | 31 August 2026 |
| Sites | 1 location across China |
Drugs / interventions tested
- Electroacupuncture
- Sham electroacupuncture
Conditions studied
- Sepsis — all drugs for Sepsis →
Sponsor
Shusheng Li
Who can join
18 and older, any sex, with Sepsis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to evaluate the efficacy and safety of electroacupuncture (EA) combined with standard Intensive Care Unit (ICU) therapy on organ dysfunction and other clinical outcomes in sepsis patients. Additionally, this study will conduct subgroup analyses to investigate the influence of septic shock and immunomodulators on the treatment effects and their correlation with electroacupuncture efficacy.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Advances in Medical Devices for Augmented Acupuncture Therapy.
Cai R, Yu C, Luo X, Xu N, et al · · 2025 · cited 1× · PMID 40679074 · DOI 10.1002/advs.202505318
Verify or expand the search:
- PubMed search for NCT06666946
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Electroacupuncture
Trials testing the same drug.
- NCT07530042 — Efficacy of Electroacupuncture Combined With Auricular Acupressure for Chronic Low Back Pain. · NA · not yet recruiting
- NCT07509294 — Effect Of Electroacupuncture With Local Anesthesia On Pain And Stress During Impacted Lower Third Molar Surgery · NA · not yet recruiting
- NCT07515027 — Electroacupuncture Plus 5-HT3 Receptor Inhibitor for PONV Prevention in High-Risk Patients Undergoing Thoracoscopic Lung · NA · recruiting
- NCT07487532 — Acupuncture for Preventing Atrial Arrhythmia Recurrence After Ablation · NA · not yet recruiting
- NCT07489625 — Hydromorphone With Electroacupuncture and Ear Acupoint Pressing for Refractory Cancer Pain · EARLY_PHASE1 · not yet recruiting
Other recruiting trials for Sepsis
Currently open trials in the same condition.
- NCT07507877 — Infraclavicular Axillary Vein Collapsibility Index as a Predictor of Fluid Responsiveness · recruiting
- NCT07154615 — Assessing Immune Dysfunction in Sepsis · recruiting
- NCT07419802 — OxiCLEAR (Oxiris Cytokines and Endotoxin Adsorption Rate) Study · recruiting
- NCT07351344 — African Survey on Sepsis Knowledge (ASK) · recruiting
- NCT07448805 — Accuracy and Safety of the Syai Tag System for Continuous Glucose Monitoring in Intensive Internal Care Unit · NA · recruiting
Other Shusheng Li trials
Trials by the same sponsor.
- NCT06879249 — The Effect of CUGP Fluid Management in Patients With Sepsis or Septic Shock · NA · completed
- NCT07090278 — Ulinastatin Treatment Reduces the Incidence of Sepsis-associated Encephalopathy · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06666946 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Shusheng Li
- Last refreshed: 18 April 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06666946.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing