Last reviewed · How we verify
NCT06666426: PUREST
This Study Will Collect Clinical and Patient Reported Experience Data From Participants Requiring Urine Output Management Overnight in the Home Setting.
NA trial testing PureWick System in Adult Nocturnal Enuresis in 171 participants. Completed in 30 June 2025.
30 June 2025
Quick facts
| Lead sponsor | C. R. Bard |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | supportive care |
| Enrollment | 171 |
| Start date | 31 October 2024 |
| Primary completion | 30 June 2025 |
| Estimated completion | 30 June 2025 |
| Sites | 15 locations across United States |
Drugs / interventions tested
- PureWick System
- Hollister Female Urinary Pouch External Collection Device
Conditions studied
- Adult Nocturnal Enuresis — all drugs for Adult Nocturnal Enuresis →
- Urinary Incontinence (UI) — all drugs for Urinary Incontinence (UI) →
Sponsor
C. R. Bard — full company profile →
Who can join
18 and older, female only, with Adult Nocturnal Enuresis or Urinary Incontinence (UI). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This post-market study will assess the performance of and user experience with the PureWick™ System in a home setting. The study will also observe safety of the study device and collect information from participants about their quality of life before and after using the device.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Safety, Efficacy, and Patient-Reported Outcomes of the PureWick™ System Versus Comparator for Nocturnal Urinary Incontinence in the Home Setting: Results of a Randomized Trial.
Medina JC, Fakih M, Khalsa S, Redmond D, et al · · 2025 · PMID 41464602 · DOI 10.3390/jcm14248699
Verify or expand the search:
- PubMed search for NCT06666426
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of PureWick System
Trials testing the same drug.
- NCT06631313 — PureWick™ Adolescent Study · NA · completed
Other C. R. Bard trials
Trials by the same sponsor.
- NCT06934486 — Observational Study of TissuePatch SF in Prevention of Air Leaks Following Lung Resection · not yet recruiting
- NCT07016698 — Real-World Registry of the Rotarex(TM) Rotational Excisional Atherectomy System (XTRACT Registry) · NA · recruiting
- NCT06850259 — This Study Will Collect Clinical and Patient Reported Satisfaction Data From Males Requiring Urine Output Management Ove · NA · completed
- NCT06669806 — Effectiveness and Safety of TIPS Stent Graft in the Treatment of Cirrhosis and Complications of Portal Hypertension · NA · recruiting
- NCT06631313 — PureWick™ Adolescent Study · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06666426 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by C. R. Bard
- Last refreshed: 24 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06666426.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing