NCT06664658

Lung Ultrasound, Cholecystectomy, Atelectasis

Completed NA Last updated 29 October 2024

What this trial tests

NA trial testing peep 5 in Laparoscopic Cholecystectomy in 60 participants. Completed in 15 September 2022.

Timeline

1 May 2022

Primary endpoint
31 August 2022

15 September 2022

Quick facts

Lead sponsor	Istanbul Medeniyet University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	60
Start date	1 May 2022
Primary completion	31 August 2022
Estimated completion	15 September 2022
Sites	2 locations across Turkey (Türkiye)

Drugs / interventions tested

• peep 5
• peep 10

Conditions studied

• Laparoscopic Cholecystectomy — all drugs for Laparoscopic Cholecystectomy →

Sponsor

Istanbul Medeniyet University

Who can join

18 and older, any sex, with Laparoscopic Cholecystectomy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Atelectasis is an important complication that can be seen during general anesthesia, especially in patients with lung problems and in patients having pneumoperitoneum. Application of PEEP during anesthesia may reduce the incidence of atelectasis.Lung ultrasonography is a tool that is easily accessible, can be applied at the bedside, is non-invasive, does not cause radiation exposure, and is increasingly used in daily practice in operating rooms. In this study, it was aimed to evaluate the occurrence of atelectasis by using lung ultrasound, and to investigate the effectiveness of ultrasound in determining the risk of developing atelectasis in patients ventilated with different PEEP values during general anesthesia. The study was conducted in 60 patients aged 18 and over, from ASA I-III groups, who were planned to undergo laparoscopic cholecystectomy surgery at the Istanbul Medeniyet University Göztepe Training and Research Hospital General Surgery Clinic, and their written and verbal informed consents were obtained. The patients included in the study were divided into 2 groups. Among the patients who were going to be operated, 5 PEEP were applied to Group I (n=30) cases, and 10 PEEP to Group II (n=30) cases during ventilation with anesthesia device. All patients were evaluated by transthoracic lung ultrasonography before anesthetic induction, after tracheal intubation, after pneumoperitoneum, and 15 minutes after recovery from anesthesia. According to the lung USG protocol, a total of 6 regions, including 2 quadrants of each hemi-thorax anterior wall, 2 right and left lateral walls, and 2 quadrants of the posterior wall, a total of 12 regions in each patient were scanned, and the images were evaluated. According to the modified lung USG scoring system, each region was scored between 0-3 consistent with the degree of atelectasis. The total score was calculated for each patient. Hemodynamic follow-up of the patients was performed. Anesthesia times, surgery times, and pneumoperitoneum times were recorded and compared.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.