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NCT06664515
Changes InMPOD After Full-thickness Macular Hole Closure
trial testing Ciro Costagliola in Full Macular Hole in 15 participants. Completed in 1 October 2024.
1 July 2023
Quick facts
| Lead sponsor | Federico II University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 15 |
| Start date | 1 June 2023 |
| Primary completion | 1 July 2023 |
| Estimated completion | 1 October 2024 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Ciro Costagliola
Conditions studied
- Full Macular Hole — all drugs for Full Macular Hole →
Sponsor
Federico II University
Who can join
Eligibility, any sex, with Full Macular Hole. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The notable increase in MPOD following successful surgery suggests its potential role as a valuable adjunctive biomarker associated with a good visual prognosis following this type of macular hole surgical interventions.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Macular Pigment Changes and Visual Recovery Following Successful Full-Thickness Macular Hole Closure Using the Inverted Flap Technique.
Rinaldi M, Galantuomo N, Passaro ML, Cennamo G, et al · · 2025 · cited 1× · PMID 39797372 · DOI 10.3390/jcm14010290
Verify or expand the search:
- PubMed search for NCT06664515
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06664515 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Federico II University
- Last refreshed: 1 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06664515.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing