Last reviewed · How we verify
NCT06657833: DEBSCAN-IVL
DEBSCAN-IVL. Drug Eluting Balloon or Drug Eluting Stent to Treat CAlcified Nodules After IntraVascular Lithotripsy.
NA trial testing Percutaneous coronary intervention of a calcified nodule with intravascular lithotripsy followed by drug eluting balloon in Coronary Artery Disease in 128 participants. Currently enrolling.
30 October 2027
Quick facts
| Lead sponsor | Fundación EPIC |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 128 |
| Start date | 17 December 2024 |
| Primary completion | 30 October 2027 |
| Estimated completion | 30 October 2027 |
| Sites | 12 locations across Spain |
Drugs / interventions tested
- Percutaneous coronary intervention of a calcified nodule with intravascular lithotripsy followed by drug eluting balloon
- Percutaneous coronary intervention of a calcified nodule with intravascular lithotripsy followed by drug eluting stent
Conditions studied
- Coronary Artery Disease — all drugs for Coronary Artery Disease →
Sponsor
Fundación EPIC — full company profile →
Who can join
18 and older, any sex, with Coronary Artery Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
International, investigator-driven, multicenter, open-label, prospective randomized controlled trial where patients with de novo lesions due to calcified nodules (CN) were randomized to drug eluting balloon (DEB) or drug eluting stents (DES).
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Coronary drug-coated balloons: Current evidence and emerging trends.
Bhandari M, Pradhan A, Behera S, Singh AK. · · 2025 · PMID 41479994 · DOI 10.4330/wjc.v17.i12.111468
Verify or expand the search:
- PubMed search for NCT06657833
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Fundación EPIC trials
Trials by the same sponsor.
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- NCT07286578 — A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Under · NA · recruiting
- NCT07190690 — Comparison of a Contemporary Sirolimus-eluting Stent (ihtDEStiny®) With Another Everolimus-eluting Stent (Xience™), Both · NA · recruiting
- NCT07256249 — Real-life Registry in Patients With Coronary Artery Disease Treated With the SELUTION Sirolimus-eluting Balloon. Selutio · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06657833 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fundación EPIC
- Last refreshed: 12 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06657833.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing