NCT06656832 (PEDAL-HF) is a NA clinical trial of Heart Failure network care in Heart Failure - NYHA II - IV, sponsored by University of Leipzig.

Who is sponsoring NCT06656832?

NCT06656832 is sponsored by University of Leipzig.

What drugs are being tested in NCT06656832?

Interventions in NCT06656832: Heart Failure network care.

What condition does NCT06656832 study?

NCT06656832 studies Heart Failure - NYHA II - IV.

Is NCT06656832 still recruiting?

NCT06656832 is currently not yet recruiting. Last updated 24 October 2024.

Last reviewed 2024-10-24 · How we verify

NCT06656832: PEDAL-HF

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Peripheral Drivers of Heart Failure Progression - the Prospective PEDAL-HF Study

Not yet recruiting NA Last updated 24 October 2024

What this trial tests

NA trial testing Heart Failure network care in Heart Failure - NYHA II - IV in 1,000 participants. Not yet recruiting.

Timeline

1 November 2024

Primary endpoint
1 October 2028

31 December 2028

Quick facts

Lead sponsor	University of Leipzig
Phase	NA
Status	Not yet recruiting
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	1,000
Start date	1 November 2024
Primary completion	1 October 2028
Estimated completion	31 December 2028

Drugs / interventions tested

Heart Failure network care

Conditions studied

Heart Failure - NYHA II - IV — all drugs for Heart Failure - NYHA II - IV →

Sponsor

University of Leipzig

Who can join

18 and older, any sex, with Heart Failure - NYHA II - IV. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

PEDAL-HF is a registry-based randomized prospective multicenter study. We plan to include 1000 patients who were recently admitted with acute decompensated heart failure at five tertiary heart clinics in Germany. For the randomised part, 750 patients will be randomized to care within a heart failure network or usual care. The primary endpoint of the randomized trial is change in NT-proBNP from baseline to 6 months of follow-up. All patients (randomized or not) will be followed for two years.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Circulating Immune Cell Signature Analysis in HFpEF Across Species.
Kneuer JM, Müller M, Erbe S, Kokot KE, et al · · 2025 · cited 2× · PMID 40709473 · DOI 10.1161/circresaha.125.326249

Verify or expand the search:

Other recruiting trials for Heart Failure - NYHA II - IV

Currently open trials in the same condition.

NCT07263035 — Urine Sodium-Driven Diuretic Adjustment Strategy in Acute Decompensated Heart Failure · Phase 4 · recruiting
NCT06885164 — Remote Monitoring of Cardiac Mechanics in Heart Failure Patients · recruiting
NCT05879887 — An Optimization Pilot to Optimize An Early Palliative Care Intervention for Advanced Heart Failure · NA · active not recruiting
NCT06901609 — Effect of Genetic Polymorphism on the Clinical Outcome to SGLT2 Inhibitors in Heart Failure Patients · active not recruiting

Other University of Leipzig trials

Trials by the same sponsor.

NCT07155564 — Validation of Energy Expenditure Measures Study · recruiting
NCT06526013 — Cholesterol Self-testing in Patients Post Acute Coronary Syndrome · NA · recruiting
NCT06420622 — INDIcators for Clarifying the bAckground of exTreme Obesity in childRen · recruiting
NCT06269263 — Feasibility of Home-based Cardiac Rehabilitation in Patients With Chronic Heart Failure (Pilot-CRHF) · NA · active not recruiting
NCT06112171 — Comparison of a Lithotripsy vs Standard Preparation Followed by Stenting With Supera Stent in Femoropopliteal Lesions · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06656832 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Leipzig
Last refreshed: 24 October 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06656832.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing