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NCT06655454
Supplemental Postoperative Bupivacaine Following Non-Surgical Endodontic Treatment
Phase 2 trial testing Supplemental Postoperative Bupivacaine in Pain Assessment in 150 participants. Currently enrolling.
30 June 2026
Quick facts
| Lead sponsor | New York University |
|---|---|
| Phase | Phase 2 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | supportive care |
| Enrollment | 150 |
| Start date | 1 November 2024 |
| Primary completion | 30 June 2026 |
| Estimated completion | 31 December 2026 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Supplemental Postoperative Bupivacaine — full drug profile →
- Placebo Injection
Conditions studied
- Pain Assessment — all drugs for Pain Assessment →
- Quality of Life (QOL) — all drugs for Quality of Life (QOL) →
- Analgesic Use — all drugs for Analgesic Use →
Sponsor
New York University
Who can join
18 and older, any sex, with Pain Assessment or Quality of Life (QOL). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study will investigate the impact of an additional injection of long-acting anesthetic on pain level, quality of life, and use of pain medication after a nonsurgical endodontic treatment. The long-acting anesthetic will be compared to a mock injection group and a group with no additional anesthetic to determine any differences in effects.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06655454
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06655454 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by New York University
- Last refreshed: 13 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06655454.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing