Last reviewed · How we verify
NCT06653439
Analgesic Effect of Bilateral Subcostal Quadratus Lumborum Block in Laparoscopic Colorectal Surgery
NA trial testing Bilateral ultrasound guided Subcostal Quadratus Lumborum Block in Anesthesia in 60 participants. Completed in 1 May 2025.
20 April 2025
Quick facts
| Lead sponsor | Ondokuz Mayıs University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 28 October 2024 |
| Primary completion | 20 April 2025 |
| Estimated completion | 1 May 2025 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Bilateral ultrasound guided Subcostal Quadratus Lumborum Block
- Control
- IV morphine PCA — full drug profile →
Conditions studied
- Anesthesia — all drugs for Anesthesia →
- Regional Anesthesia — all drugs for Regional Anesthesia →
- Post Operative Pain — all drugs for Post Operative Pain →
Sponsor
Ondokuz Mayıs University
Who can join
Adults 18 to 75, any sex, with Anesthesia or Regional Anesthesia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Effective postoperative pain management is crucial for promoting early recovery and ambulation following laparoscopic colorectal surgery. Regional anesthesia techniques, like interfascial plane blocks, are increasingly being used to achieve this. The quadratus lumborum block (QLB) is a relatively new approach in abdominal surgeries, providing significant pain relief by blocking both somatic and sympathetic nerves. In particular, the anterior QLB technique allows local anesthetic to spread to the thoracic paravertebral space, making it potentially more effective for postoperative analgesia. The hypothesis of this study is that bilateral subcostal anterior QLB can reduce both postoperative pain and opioid consumption in laparoscopic colorectal surgery.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Efficacy of anterior subcostal quadratus lumborum block for postoperative analgesia in laparoscopic colorectal surgery: a randomized controlled trial.
Turunc E, Dost B, Kaya C, Ustun YB, et al · · 2025 · PMID 41151981 · DOI 10.1136/rapm-2025-107136
Verify or expand the search:
- PubMed search for NCT06653439
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06653439 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ondokuz Mayıs University
- Last refreshed: 15 June 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06653439.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing