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NCT06653413

Exploring the Diagnostic Performance of Dynamic Chest Radiology in Chronic Obstructive Pulmonary Disease

ENROLLING BY INVITATION Last updated 23 October 2024
What this trial tests

trial in Chronic Obstructive Pulmonary Disease (COPD) in 600 participants. Enrolling by invitation.

Timeline
1 January 2024
Primary endpoint
1 January 2024
30 December 2026

Quick facts

Lead sponsorNanfang Hospital, Southern Medical University
StatusENROLLING BY INVITATION
Study typeOBSERVATIONAL
Enrollment600
Start date1 January 2024
Primary completion1 January 2024
Estimated completion30 December 2026
Sites1 location across China

Conditions studied

Sponsor

Nanfang Hospital, Southern Medical University

Who can join

Adults 40 to 80, any sex, with Chronic Obstructive Pulmonary Disease (COPD). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The prevalence of chronic obstructive pulmonary disease (COPD) is on the rise, leading to an increasing economic and social burden. Currently, the diagnosis and staging of COPD heavily rely on pulmonary function testing. However, limitations such as patient cooperation and comorbidities can hinder accurate diagnosis. In situations like a respiratory pandemic, pulmonary function testing may not be feasible. Dynamic chest radiography has emerged as a promising area of research due to its quick procedure, high patient cooperation, low risk, minimal radiation exposure, and reduced direct contact. Recent clinical studies have started to explore the relationship between dynamic chest X-ray measurements and lung function parameters. However, there is a noticeable scarcity of research focusing on the use of dynamic chest X-ray in aiding the diagnosis of COPD, particularly in Chinese populations where cohort data is lacking. Consequently, there is a pressing need to investigate the correlation between various dynamic chest radiograph parameters and lung function indicators, as well as their potential diagnostic value in COPD.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Dynamic Chest Radiography as an Alternative to Pulmonary Function Tests for Chronic Obstructive Pulmonary Disease.
    Yu D, Xie W, Guo Y, Zhu X, et al · · 2025 · PMID 41400467 · DOI 10.1148/radiol.251296

Verify or expand the search:

Other recruiting trials for Chronic Obstructive Pulmonary Disease (COPD)

Currently open trials in the same condition.

Other Nanfang Hospital, Southern Medical University trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

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