NCT06652984

Effectiveness of Mobile Respiratory Training in Ankylosing Spondylitis

Completed NA Last updated 8 July 2025

What this trial tests

NA trial testing Exercise 1 in Ankylosing Spondylitis in 80 participants. Completed in 22 May 2025.

Timeline

5 November 2024

Primary endpoint
12 May 2025

22 May 2025

Quick facts

Lead sponsor	Uşak University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	supportive care
Enrollment	80
Start date	5 November 2024
Primary completion	12 May 2025
Estimated completion	22 May 2025
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

• Exercise 1
• Exercise 2

Conditions studied

• Ankylosing Spondylitis — all drugs for Ankylosing Spondylitis →
• Respiratory Distress — all drugs for Respiratory Distress →
• Exercise Therapy — all drugs for Exercise Therapy →
• Breath Tests — all drugs for Breath Tests →

Sponsor

Uşak University

Who can join

Adults 18 to 50, any sex, with Ankylosing Spondylitis or Respiratory Distress. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Introduction and aim; Low functionality of respiratory muscles is frequently observed in various diseases such as chronic obstructive pulmonary disease, cystic fibrosis, idiopathic pulmonary fibrosis, and rheumatological diseases such as ankylosing spondylitis. Strengthening the respiratory muscles is a part of the treatment in such disease groups, and it has been reported that the quality of life of patients increases with the improvement in the respiratory muscles. Stavrou et al. In a study published in 2021, they achieved an increase in VO2max and maximum respiratory power in athletes after an exercise program with the AirOFit PRO™ (AirOFit, Copenhagen, Denmark) branded mobile breathing exercise device, which they introduced as a new technology. However, there is no study yet reporting the use of this device in rheumatological diseases.

The aim of this study is to investigate the effects of personalized breathing exercises with the AirOFit PRO™ (AirOFit, Copenhagen, Denmark) branded mobile breathing exercise device on respiratory muscles and functional exercise capacity, as well as on specific outcomes of the disease, in patients with ankylosing spondylitis.

Hypotheses of the study;

a) Hypothesis H1: Personalised breathing exercises applied with a mobile respiratory exercise device in patients with ankylosing spondylitis have a positive effect on respiratory capacity and activities of daily living in patients.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Effectiveness of a mobile respiratory trainer (AiroFit PRO<sup>™</sup>) in ankylosing spondylitis: a randomized controlled trial.
   Uçar Baytaroğlu İM, Karahan AY. · · 2025 · PMID 41190581 · DOI 10.1080/07853890.2025.2582913