Last reviewed · How we verify
NCT06652828: TRAIL
Perturbation-Based Treadmill Training to Prevent Unrecovered Falls in Geriatric Patients
NA trial testing Conventional Treadmill Walking (CTT) in Fall Prevention in 396 participants. Currently enrolling.
30 April 2027
Quick facts
| Lead sponsor | University of Oldenburg |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 396 |
| Start date | 25 November 2024 |
| Primary completion | 30 April 2027 |
| Estimated completion | 30 April 2027 |
| Sites | 3 locations across Germany |
Drugs / interventions tested
- Conventional Treadmill Walking (CTT)
- Perturbation-Based Balance Training (PBT)
Conditions studied
- Fall Prevention — all drugs for Fall Prevention →
- Exercise — all drugs for Exercise →
- Geriatrics — all drugs for Geriatrics →
- Cognitive Impairment — all drugs for Cognitive Impairment →
Sponsor
University of Oldenburg
Who can join
70 and older, any sex, with Fall Prevention or Exercise. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to determine the effectiveness of perturbation-based balance training (PBT) in preventing unrecovered falls among geriatric patients aged ≥70 years with a prospective fall risk of ≥40%. The study will also assess the safety and feasibility of PBT. The main research questions are: A total of 396 participants will receive 9 training sessions of either PBT or conventional treadmill training and will attend an assessment before and after the intervention, as well as 6 and 12 months follow up. Falls will be documented throughout the entire study period using calendars, telephone interviews, and proxy information. The primary outcome, unrecovered falls, will be recorded after the end of the intervention until 12 months follow up.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Treadmill perturbation-based balance training to prevent unrecovered falls in fall-prone older adults with and without cognitive impairment: protocol for the multi-center randomized controlled TRAIL study.
Koschate-Storm J, Werner C, Bartel J, Bauer JM, et al · · 2025 · PMID 41436967 · DOI 10.1186/s12877-025-06599-w
Verify or expand the search:
- PubMed search for NCT06652828
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Fall Prevention
Currently open trials in the same condition.
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- NCT06745544 — Impact of Screening and Multicomponent Exercise on Fall Rates, Fractures, and Cardiovascular Health in Diabetes · NA · recruiting
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Other University of Oldenburg trials
Trials by the same sponsor.
- NCT06525805 — Readers' Attention of Shorter Versus Longer Abstracts of Systematic Reviews · NA · completed
- NCT04968223 — Neural Correlates of Social Touch and Interoceptive Perception As Potential Biomarker for Impaired Social Functioning · completed
- NCT04832750 — Depression-Reduction by Accelerated Personalized NeuroModulation and Its Effects on Sleep · completed
- NCT04770038 — Social Integration During Psychiatric Inpatient Therapy as Predictor of Treatment Response · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06652828 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Oldenburg
- Last refreshed: 14 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06652828.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing