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NCT06650631
The Effectiveness of Heat Treatment on Knee Pain in Patients With Osteoarthritis - an International, Multicenter Clinical Investigation
NA trial testing Knee Heatwraps in Pain Management in 80 participants. Currently enrolling.
29 August 2025
Quick facts
| Lead sponsor | Aziende Chimiche Riunite Angelini Francesco S.p.A |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 80 |
| Start date | 21 October 2024 |
| Primary completion | 29 August 2025 |
| Estimated completion | 29 August 2025 |
| Sites | 1 location across Switzerland |
Drugs / interventions tested
- Knee Heatwraps
Conditions studied
- Pain Management — all drugs for Pain Management →
- Osteoarthritis — all drugs for Osteoarthritis →
Sponsor
Aziende Chimiche Riunite Angelini Francesco S.p.A — full company profile →
Who can join
Adults 19 to 69, any sex, with Pain Management or Osteoarthritis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This post-market clinical follow-up, open-label, multicenter clinical investigation is designed to investigate the effectiveness, safety and tolerability of ThermaCare® Knee Heatwraps in the painful knee joint due to osteoarthritis. Approximately 80 patients, 19-69 years old inclusive, with moderate knee osteoarthritis (without acute flares or inflammation) will be enrolled. The overall duration of the investigation is expected to be 11 days, including screening days. The maximum treatment duration for each patient is 7 days (8h/d).
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06650631
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Other Aziende Chimiche Riunite Angelini Francesco S.p.A trials
Trials by the same sponsor.
- NCT07199543 — Palatability Study of Five Formulations of Benzydamine HCl Lozenges · Phase 1 · completed
- NCT06922175 — REACH: RWE Retrospective Study to Evaluate Cenobamate Impact on Health Care Resource Utilization · recruiting
- NCT06773767 — Bioavailability of Trazodone Hydrochloride (New Polymer) vs. Trazodone Hydrochloride Contramid® at Steady-state. · Phase 1 · completed
- NCT05867160 — Adjunctive Anti-seizure Medication (ASM) Real World Evidence (RWE) Study · active not recruiting
- NCT06111118 — The Effectiveness of Sustained Heat Treatment on Delayed-Onset Muscle Soreness (DOMS) · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06650631 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Aziende Chimiche Riunite Angelini Francesco S.p.A
- Last refreshed: 8 September 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06650631.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing