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NCT06643663
Role of GTR on Healing Outcome & Quality of Life in Combined Endo Perio Lesions With Communication
NA trial testing Endodontic Micro-Surgery in Periapical Diseases in 30 participants. Currently enrolling.
23 December 2025
Quick facts
| Lead sponsor | Postgraduate Institute of Dental Sciences Rohtak |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 23 May 2024 |
| Primary completion | 23 December 2025 |
| Estimated completion | 23 December 2025 |
| Sites | 1 location across India |
Drugs / interventions tested
- Endodontic Micro-Surgery
Conditions studied
- Periapical Diseases — all drugs for Periapical Diseases →
- Endodontic Disease — all drugs for Endodontic Disease →
Sponsor
Postgraduate Institute of Dental Sciences Rohtak
Who can join
16 and older, any sex, with Periapical Diseases or Endodontic Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The recovery of periapical defects linked to periodontal communication frequently yields less satisfactory results. Numerous studies and case reports have highlighted the notable success achieved through the application of guided tissue regeneration techniques. More recently, autologous platelet concentrate plug \& placental membrane have emerged as a treatment option for addressing such lesions. Nevertheless, there has been no study using PRF-Medium with ACM membrane on the healing of aforesaid lesion \& quality of life assessment.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06643663
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Endodontic Micro-Surgery
Trials testing the same drug.
- NCT07048171 — TO DETERMINE THE EFFECT OF ALLOGRAFT AND iPRF WITH OR WITHOUT COLLAGEN MEMBRANE ON HEALING OF APICOMARGINAL DEFECTS · NA · recruiting
Other recruiting trials for Periapical Diseases
Currently open trials in the same condition.
- NCT07448571 — Evaluation of Revitalization Success Using i-PRF in Non-Surgical Root Canal Retreatment · NA · recruiting
- NCT06252337 — Survival and Success of Two Different Filling Techniques · NA · active not recruiting
- NCT05888935 — Detection of Periapical Lesions on Dental Panoramic Radiographs Based on Artificial Intelligence · recruiting
Other Postgraduate Institute of Dental Sciences Rohtak trials
Trials by the same sponsor.
- NCT07412067 — Healing of Apicomarginal Defects Using Autograft or Allograft With Collagen Membrane · NA · not yet recruiting
- NCT07381595 — Role of Subgingival Instrumentation in Oral Lichen Planus · NA · not yet recruiting
- NCT07300124 — Outcome of Direct Pulp Capping and Partial Pulpotomy in Reversible Pulpitis · NA · not yet recruiting
- NCT07506135 — Effect of Aromatherapy on Pain and Anxiety During Orthodontic Extraction of Maxillary Premolars. · NA · completed
- NCT07179835 — To Evaluate Periapical Healing Post Full Pulpotomy in Teeth With and Without Apical Periodontitis · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06643663 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Postgraduate Institute of Dental Sciences Rohtak
- Last refreshed: 8 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06643663.
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