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NCT06641505
Feasibility of Deep Inspiratory Internal Jugular Vein Variability in Guiding Preoperative Fluid Replacement
NA trial testing Guiding rehydration in Hemodynamic in 80 participants. Currently enrolling.
1 June 2025
Quick facts
| Lead sponsor | Affiliated Hospital of Jiaxing University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 80 |
| Start date | 1 August 2024 |
| Primary completion | 1 June 2025 |
| Estimated completion | 1 June 2025 |
| Sites | 1 location across China |
Drugs / interventions tested
- Guiding rehydration
Conditions studied
- Hemodynamic — all drugs for Hemodynamic →
Sponsor
Affiliated Hospital of Jiaxing University
Who can join
Adults 60 to 80, any sex, with Hemodynamic. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Compare the incidence of hypotension during the propofol-induced period between the internal jugular vein variability-guided fluid infusion group and the conventional fluid infusion group through a fluid infusion experiment before anesthesia induction, so as to evaluate the feasibility of using the internal jugular vein variability under deep inspiration to guide preoperative fluid infusion.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effects of liquid resuscitation guided by internal jugular vein variability during deep inhalation on preventing propofol-induced hypotension in elderly patients.
Wei XL, Xi YZ, Xie L, Li ZP, et al · · 2025 · PMID 40676549 · DOI 10.1186/s12871-025-03227-3
Verify or expand the search:
- PubMed search for NCT06641505
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Affiliated Hospital of Jiaxing University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06641505 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Affiliated Hospital of Jiaxing University
- Last refreshed: 15 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06641505.
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