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NCT06639555

Initial Clinical and CBCT Outcomes of Enamel Matrix Derivative-Based Regenerative Therapy in Vertical Bone Defects

Completed NA Last updated 15 October 2024
What this trial tests

NA trial testing PRP( platelet rich plasma) in Vertical Alveolar Bone Loss in 48 participants. Completed in 15 August 2023.

Timeline
24 June 2022
Primary endpoint
15 February 2023
15 August 2023

Quick facts

Lead sponsorTsvetalina Gerova-Vatsova
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposetreatment
Enrollment48
Start date24 June 2022
Primary completion15 February 2023
Estimated completion15 August 2023
Sites1 location across Bulgaria

Drugs / interventions tested

Conditions studied

Sponsor

Tsvetalina Gerova-Vatsova

Who can join

Adults 18 to 65, any sex, with Vertical Alveolar Bone Loss. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Study of the effectiveness of the application of regenerative therapy with autogenous, platelet-rich plasma in vertical defects Investigation of the effectiveness of the application of regenerative therapy with enamel matrix derivatives in vertical bone defects Study of the effectiveness of the application of guided tissue regeneration in vertical bone defects with Barrier membrane and Barrier membrane and autogenous platelet-rich plasma

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Beyond Bone Grafts: Exploring the Efficacy of Alternative Regenerative Therapies.
    Gerova-Vatsova T. · · 2024 · cited 1× · PMID 39677141 · DOI 10.7759/cureus.73745

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing