Last reviewed · How we verify
NCT06639555
Initial Clinical and CBCT Outcomes of Enamel Matrix Derivative-Based Regenerative Therapy in Vertical Bone Defects
NA trial testing PRP( platelet rich plasma) in Vertical Alveolar Bone Loss in 48 participants. Completed in 15 August 2023.
15 February 2023
Quick facts
| Lead sponsor | Tsvetalina Gerova-Vatsova |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 48 |
| Start date | 24 June 2022 |
| Primary completion | 15 February 2023 |
| Estimated completion | 15 August 2023 |
| Sites | 1 location across Bulgaria |
Drugs / interventions tested
- PRP( platelet rich plasma)
- EMD (Enamel Matrix Derivative)
- Guided Tissue Regeneration (barrier membrane)
- Guided Tissue Regeneration(barrier membrane and PRP)
Conditions studied
- Vertical Alveolar Bone Loss — all drugs for Vertical Alveolar Bone Loss →
Sponsor
Tsvetalina Gerova-Vatsova
Who can join
Adults 18 to 65, any sex, with Vertical Alveolar Bone Loss. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Study of the effectiveness of the application of regenerative therapy with autogenous, platelet-rich plasma in vertical defects Investigation of the effectiveness of the application of regenerative therapy with enamel matrix derivatives in vertical bone defects Study of the effectiveness of the application of guided tissue regeneration in vertical bone defects with Barrier membrane and Barrier membrane and autogenous platelet-rich plasma
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Beyond Bone Grafts: Exploring the Efficacy of Alternative Regenerative Therapies.
Gerova-Vatsova T. · · 2024 · cited 1× · PMID 39677141 · DOI 10.7759/cureus.73745
Verify or expand the search:
- PubMed search for NCT06639555
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06639555 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Tsvetalina Gerova-Vatsova
- Last refreshed: 15 October 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06639555.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing