Who is sponsoring NCT06639204?

NCT06639204 is sponsored by Damascus University.

What drugs are being tested in NCT06639204?

Interventions in NCT06639204: Electrical stimulation, Orthodontic treatment without acceleration.

What condition does NCT06639204 study?

NCT06639204 studies Class II Division 1 Malocclusion.

Is NCT06639204 still recruiting?

NCT06639204 is currently completed. Last updated 14 January 2025.

Last reviewed 2025-01-14 · How we verify

NCT06639204

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Cephalometric Changes Following Retraction of the Upper Anterior Teeth Stimulated by Low-intensity Electrical Current

Completed NA Last updated 14 January 2025

What this trial tests

NA trial testing Electrical stimulation in Class II Division 1 Malocclusion in 36 participants. Completed in 1 December 2023.

Timeline

1 May 2023

Primary endpoint
15 November 2023

1 December 2023

Quick facts

Lead sponsor	Damascus University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	36
Start date	1 May 2023
Primary completion	15 November 2023
Estimated completion	1 December 2023
Sites	1 location across Syria

Drugs / interventions tested

Electrical stimulation
Orthodontic treatment without acceleration

Conditions studied

Class II Division 1 Malocclusion — all drugs for Class II Division 1 Malocclusion →

Sponsor

Damascus University

Who can join

Adults 18 to 25, any sex, with Class II Division 1 Malocclusion. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Thirty-six patients requiring extraction of maxillary first premolars and en-masse retraction of upper anterior teeth will participate in the study. They will be randomly assigned into two groups: low-intensity electrical stimulation group (LIES) and traditional retraction group (TRAD) after the leveling and alignment phase is completed. En-masse retraction will be initiated in both groups via closed nickel-titanium coil springs that applying 250 g of force on each side, Mini-implants will be inserted to provide the highest level of anchorage. The skeletal, dental, and soft tissue changes will be detected using lateral cephalometric radiographs, which will be obtained pretreatment, pre-, and post-en-masse retraction of the anterior teeth.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Evaluation of the skeletal, dental, and soft-tissue changes after the en-masse retraction of upper anterior teeth stimulated by low-intensity electrical current: a randomized controlled clinical trial.
Shaadouh RI, Hajeer MY, Alam MK, Sultan K, et al · · 2025 · cited 1× · PMID 40462109 · DOI 10.1186/s12903-025-06316-4

Verify or expand the search:

Other trials of Electrical stimulation

Trials testing the same drug.

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NCT06303427 — Effects of Modified Constraint-induced Movement Therapy With and Without Electrical Stimulation in Erb's Palsy · NA · completed

Other Damascus University trials

Trials by the same sponsor.

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NCT07515612 — The Impact of Valerian and Chamomile on Children's Anxiety in the Dental Clinic. · NA · recruiting
NCT07272798 — Cardiac Self-Efficacy in Patients With Chronic Thromboembolic Pulmonary Hypertension · recruiting
NCT07426523 — Effectiveness of Needle-Free Infiltration Anesthesia in Reduction of Dental Pain and Anxiety During Local Anesthesia. · NA · completed
NCT07366788 — Clinical Outcomes of Mandibular Primary Molar Extraction Using Physics Forceps in Children · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06639204 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Damascus University
Last refreshed: 14 January 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06639204.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing