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NCT06638957

Impact of the COVID-19 Pandemic on Oncologic Outcomes in Colorectal Cancer

Completed Last updated 15 October 2024
What this trial tests

trial in Colorectal Carcinoma in 14,951 participants. Completed in 20 September 2024.

Timeline
1 January 2018
Primary endpoint
31 December 2020
20 September 2024

Quick facts

Lead sponsorIn Ja Park
StatusCompleted
Study typeOBSERVATIONAL
Enrollment14,951
Start date1 January 2018
Primary completion31 December 2020
Estimated completion20 September 2024
Sites1 location across South Korea

Conditions studied

Sponsor

In Ja Park

Who can join

Eligibility, any sex, with Colorectal Carcinoma or COVID 19. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this observational study is to assess the impact of the COVID-19 pandemic on colorectal cancer (CRC) outcomes, particularly focusing on stage distribution and recurrence-free survival in patients undergoing surgery at eight tertiary care institutions in Korea from 2018 to 2020. Main Question Does the COVID-19 pandemic lead to more advanced stages of colorectal cancer at diagnosis and higher complication rates during surgery? Is there a significant difference in recurrence-free survival between CRC patients treated before and during the pandemic? This study found that more patients presented with advanced-stage CRC during the COVID-19 pandemic, with significantly higher rates of tumor-related complications (perforations, abscesses, and preoperative obstructions), as well as an increase in open surgeries and combined resections. No significant difference in recurrence-free survival was observed between the pre-COVID-19 and COVID-19 periods, although postoperative complication rates were higher, especially among rectal cancer patients and those receiving preoperative chemoradiotherapy.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06638957.

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