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NCT06636643
The Effect of Bone Marrow Stem Cells Harvested from the Iliac Crest Versus Mandibular Ramus in Alveolar Cleft Regeneration
trial in Cleft Lip and Palate in 12 participants. Completed in 29 May 2024.
20 May 2021
Quick facts
| Lead sponsor | Faculty of Dental Medicine for Girls |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 12 |
| Start date | 15 April 2021 |
| Primary completion | 20 May 2021 |
| Estimated completion | 29 May 2024 |
| Sites | 1 location across Egypt |
Conditions studied
- Cleft Lip and Palate — all drugs for Cleft Lip and Palate →
Sponsor
Faculty of Dental Medicine for Girls — full company profile →
Who can join
Eligibility, any sex, with Cleft Lip and Palate. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This comparative and prospective study was conducted on 10 patients with alveolar cleft defects. Patients with alveolar cleft defects were randomly selected and randomly divided into two equal groups: Group A: received Autologous (BMMSCs) harvested from the mandibular ramus and seeded on a collagen sponge in combination with nanohydroxyapatite. Group B: received Autologous (BMMSCs) harvested from the lilac crest and seeded on a collagen sponge in combination with nanohydroxyapatite.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Craniomaxillofacial-Derived MSCs in Congenital Defect Reconstruction.
Song X, Peng L, Bian Z, Yin W. · · 2025 · PMID 40723825 · DOI 10.3390/biom15070953
Verify or expand the search:
- PubMed search for NCT06636643
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other Faculty of Dental Medicine for Girls trials
Trials by the same sponsor.
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- NCT06713174 — Interleukin 8 and10 Levels Changes in Teeth With Necrotic Pulp and Apical Periodontitis · NA · completed
- NCT06805604 — Digital Techniques · Phase 1 · active not recruiting
- NCT06941246 — Prolactin Levels in Type 2 Diabetic Patients With Stage III Periodontitis · NA · completed
- NCT06945562 — Influence of Collagen Cone on Jumping Gap Management Around Dental Implants · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06636643 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Faculty of Dental Medicine for Girls
- Last refreshed: 10 October 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06636643.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing