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NCT06634888
Root Resorption and Alveolar Bone in the Maxillary Canine Retraction Using Injectable Platelet-rich Fibrin: A Split-Mouth Trial
NA trial testing Injectable platelet rich fbirin in Angle Class I in 31 participants. Completed in 27 May 2024.
27 May 2024
Quick facts
| Lead sponsor | Can Tho University of Medicine and Pharmacy |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | other |
| Enrollment | 31 |
| Start date | 27 August 2022 |
| Primary completion | 27 May 2024 |
| Estimated completion | 27 May 2024 |
| Sites | 1 location across Vietnam |
Drugs / interventions tested
- Injectable platelet rich fbirin
- Injectable platelet rich fbirin
Conditions studied
- Angle Class I — all drugs for Angle Class I →
Sponsor
Can Tho University of Medicine and Pharmacy
Who can join
Adults 15 to 25, any sex, with Angle Class I. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Prolonged orthodontic treatment is a risk factor for root resorption, so accelerating the speed of tooth movement using different methods can limit tooth root resorption. There are multiple factors causing root resorption, such as orthodontic force level, treatment duration, and methods of quantification of root resorption. PRF, a completely autologous fibrin matrix, was developed as a second-generation platelet concentrate without adding anticoagulants and additives. The injectable platelet-rich fibrin is the liquid form of the substance obtained through low-speed centrifugation. It has many advantages over the conventional form, such as higher rates of regenerative cells and growth factors. In the present study, Cone Beam Computed Tomography (CBCT) was used as a measurement tool for root resorption. CBCT is a helpful tool for evaluating changes in the root length of teeth and surrounding bone tissue.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06634888
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Related trials
Other trials of Injectable platelet rich fbirin
Trials testing the same drug.
- NCT06562452 — Evaluating the Effect of Injectable Platelet Rich Fibrin on Tooth Movement · NA · completed
Other Can Tho University of Medicine and Pharmacy trials
Trials by the same sponsor.
- NCT07305077 — One-Minute Preceptor to Improve Bedside Teaching · NA · recruiting
- NCT07155018 — Micro-Osteoperforations to Accelerate Maxillary Canine Retraction in Class I Malocclusion · NA · completed
- NCT07260006 — Treatment Efficacy of Regimens With and Without Bismuth in Children With Helicobacter Pylori-Associated Peptic Ulcer Dis · NA · recruiting
- NCT07176871 — Comparing HANT and Conventional NiTi Archwires in Alignment · NA · completed
- NCT06963788 — The Comparative Effects of Using 0.12% Chlorhexidine and Silver Nanoparticles Mouthwashes in Medical Students · Phase 3 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06634888 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Can Tho University of Medicine and Pharmacy
- Last refreshed: 10 October 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06634888.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing