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NCT06633614: PREPARE@HOME
PREhabilitation of Frail Elderly PAtients Undergoing majoR surgEry at HOME (PREPARE-HOME) Using Smart Wearables
NA trial testing Supervised prehabilitation programme in Frailty Syndrome in 190 participants. Not yet recruiting.
30 September 2027
Quick facts
| Lead sponsor | Singapore General Hospital |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 190 |
| Start date | 1 August 2025 |
| Primary completion | 30 September 2027 |
| Estimated completion | 31 January 2028 |
Drugs / interventions tested
- Supervised prehabilitation programme
Conditions studied
- Frailty Syndrome — all drugs for Frailty Syndrome →
Sponsor
Singapore General Hospital
Who can join
65 and older, any sex, with Frailty Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to evaluate whether a prehabilitation program using wearable technology can improve physical function and postoperative outcomes in elderly patients (65 years or older) undergoing major elective non-cardiac surgery. The main questions it aims to answer are: Does the prehabilitation program improve physical function, as measured by the 6-minute walk test (6MWT), from baseline to pre-surgery? Does the prehabilitation program reduce postoperative complications and enhance recovery? Researchers will compare participants who receive the prehabilitation program with wearable technology (intervention group) to those receiving standard preoperative care (control group) to see if the intervention results in greater improvements in physical function and postoperative outcomes. Participants will: Follow a personalized exercise program monitored remotely via telemedicine. Wear a Fitbit Aspire 3 device to track vital signs such as heart rate and physical activity. Undergo assessments of physical function and quality of life before surgery.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Prehabilitation of frail elderly PAtients undergoing majoR surgEry at HOME (PREPARE-HOME): a superiority parallel-group randomised controlled trial protocol evaluating smart wearable enhanced prehabilitation versus usual care.
Leong YH, Tay VYJ, Yang X, Tan CJ, et al · · 2025 · PMID 41130682 · DOI 10.1136/bmjopen-2024-094986
Verify or expand the search:
- PubMed search for NCT06633614
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Frailty Syndrome
Currently open trials in the same condition.
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- NCT07338929 — Physical Performance Assessment in Kidney Transplant Evaluation · recruiting
- NCT07071142 — Frailty and Outcomes in Older Heart Failure Patients With Ejection Fraction >40% · active not recruiting
Other Singapore General Hospital trials
Trials by the same sponsor.
- NCT07452159 — Diabetes In Asians at Risk in Youth · not yet recruiting
- NCT07527247 — Improving Vaccine Protection for Older Adults · Phase 2 · recruiting
- NCT07533188 — Patient Outcomes Following Kinematic and Functional Alignment in Robotic-Assisted Total Knee Arthroplasty With Randomize · NA · recruiting
- NCT07042061 — Trial of Mobile External Defibrillator for Out-of-hospital Cardiac Arrest in Singapore. · NA · not yet recruiting
- NCT07099040 — Community-based Multi-domain Intervention to Detect and Delay Cognitive Decline in Community-dwelling Older Adults: A Pi · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06633614 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Singapore General Hospital
- Last refreshed: 15 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06633614.
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