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NCT06629025
The Clinical Manifestation and Prognosis of Pediatric Esophageal Motility Disorders
trial testing High-resolution impedance manometry in Esophageal Motility Disorders in 10 participants. Completed in 5 February 2024.
5 February 2024
Quick facts
| Lead sponsor | National Taiwan University Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 10 |
| Start date | 15 March 2023 |
| Primary completion | 5 February 2024 |
| Estimated completion | 5 February 2024 |
| Sites | 1 location across Taiwan |
Drugs / interventions tested
- High-resolution impedance manometry
Conditions studied
- Esophageal Motility Disorders — all drugs for Esophageal Motility Disorders →
Sponsor
National Taiwan University Hospital
Who can join
Adults 0 to 20, any sex, with Esophageal Motility Disorders. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Background: Abnormal esophageal peristalsis mostly occurs in adults, but some patients have onset in childhood. Most of the symptoms of esophageal motility disorders in children are not as clear as those described by adult patients, and they are only manifested in repeated vomiting. Esophageal peristalsis abnormalities in children took longer from symptoms to diagnosis than in adults. Common esophageal motility disorders in children include Achalasia, ineffective esophageal motility disorder (IEM), absent contractility, nutcracker esophagus, jackhammer esophagus, diffuse Esophageal spasm (diffuse esophageal spasm), lower esophageal sphincter hypertension (hypertensive lower esophageal sphincter), etc. Treatment for abnormal esophageal motility includes medication, endoscopic therapy, and surgery. This includes peroral endoscopic myotomy (POEM). The above treatment effects are rarely reported in children. This project uses the method of retrospective analysis of medical records to study the clinical manifestations and treatment prognosis of abnormal esophageal motility in children Research purpose: The purpose of this study is to evaluate various clinical manifestations and treatment prognosis of abnormal esophageal motility in children, including analysis of diagnosis age, symptom time, related imaging examinations, endoscopy and high-resolution esophageal pressure examination, treatment methods, etc. Research design: We plan to collect pediatric patients (0-20 years old) diagnosed with abnormal esophageal peristalsis at National Taiwan University Hospital during 2010/1/1-2022/12/31. Retrospective analysis of medical records and relevant laboratory data of patients in hospitals, including gender, height and weight, age of onset, symptoms, clinical manifestations, endoscopy, gastrointestinal photography, 24-hour multi-lumen esophageal impedance and acid-base examination, high-resolution esophageal pressure examination, ultrasound examination, pathological slide report, treatment response, etc. Expected results: Analyze the clinical symptoms and different treatment methods of abnormal esophageal motility in children, and understand the development and prognosis of abnormal esophageal motility in children. Key words: Esophageal motility disorders in children; High-resolution esophageal manometry; Esophageal achalasia
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06629025
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Related trials
Other recruiting trials for Esophageal Motility Disorders
Currently open trials in the same condition.
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- NCT05455359 — Gastrointestinal Dysmotility on Aspiration Risk · Phase 4 · recruiting
- NCT05380791 — Effect of Esophageal Contractile Reserve on Changes in Esophageal Motility and Symptoms After ARS in Patients With GERD · recruiting
- NCT05272046 — Monopolar and Bipolar Current RFA Knife in POEM · NA · active not recruiting
Other National Taiwan University Hospital trials
Trials by the same sponsor.
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- NCT07317310 — The NTU JO-SMART Study · NA · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06629025 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Taiwan University Hospital
- Last refreshed: 8 October 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06629025.
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