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NCT06624891
Interest of the Pleth Variability Index in Neurosurgery
NA trial testing perioperative fluid responsiveness with the Pleth variability index in Intraoperative Monitoring in 70 participants. Completed in 19 August 2024.
30 June 2024
Quick facts
| Lead sponsor | National Institute of Neurology, Tunisia |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 70 |
| Start date | 1 March 2023 |
| Primary completion | 30 June 2024 |
| Estimated completion | 19 August 2024 |
| Sites | 1 location across Tunisia |
Drugs / interventions tested
- perioperative fluid responsiveness with the Pleth variability index
- perioperative fluid responsiveness with delta PP
Conditions studied
- Intraoperative Monitoring — all drugs for Intraoperative Monitoring →
- Hypovolemia — all drugs for Hypovolemia →
- Fluid Challenge — all drugs for Fluid Challenge →
Sponsor
National Institute of Neurology, Tunisia
Who can join
18 and older, any sex, with Intraoperative Monitoring or Hypovolemia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This clinical trial aims to study the interest of the Pleth Variability Index (PVI) to evaluate perioperative fluid responsiveness in neurosurgery in adults. The main question it aims to answer is: • Does the Pleth variability index predict fluid responsiveness in neurosurgery? Researchers will compare the Pleth variability index to dela PP to see if it predicts fluid responsiveness in neurosurgery. Once participants give their consent, they will be randomly assigned to one of two groups. In one group, fluid responsiveness will be monitored using the Pleth Variability Index, while in the other group, it will be monitored using delta PP.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06624891
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06624891 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Institute of Neurology, Tunisia
- Last refreshed: 3 October 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06624891.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing