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NCT06624631: PDMC-SL
PDMC Implementation Trial in Kenya
Phase 4 trial testing SMS reminders; adherence support strategy a in Severe Malaria in 600 participants. Currently enrolling.
30 September 2026
Quick facts
| Lead sponsor | Liverpool School of Tropical Medicine |
|---|---|
| Phase | Phase 4 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 600 |
| Start date | 5 September 2025 |
| Primary completion | 30 September 2026 |
| Estimated completion | 30 September 2026 |
| Sites | 1 location across Kenya |
Drugs / interventions tested
- SMS reminders; adherence support strategy a
- Community Health Promoters (CHP) home visits; adherence support strategy b
- No reminders; adherence support strategy c
Conditions studied
- Severe Malaria — all drugs for Severe Malaria →
- Severe Anemia — all drugs for Severe Anemia →
Sponsor
Liverpool School of Tropical Medicine
Who can join
Under 9, any sex, with Severe Malaria or Severe Anemia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this implementation trial is to evaluate at least two alternative delivery strategies and adherence support for malaria chemoprevention with dihydroartemisinin-piperaquine in the post-discharge management of children hospitalised with severe anaemia or severe malaria to optimise adherence in Kenya. The actual interventions to be evaluated have been co-designed with national stakeholders during an initial formative research stage.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06624631
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Severe Malaria
Currently open trials in the same condition.
- NCT06601712 — Post-discharge Malaria Chemoprevention Implementation Trial in Benin · Phase 4 · recruiting
- NCT05711485 — Platelet-Directed Whole Blood Transfusion Strategy for Malaria · NA · recruiting
Other Liverpool School of Tropical Medicine trials
Trials by the same sponsor.
- NCT07403318 — Mobile Health Supported Self-care Among Tertiary Education Students in Zimbabwe · NA · not yet recruiting
- NCT06944275 — Characterising the Loss of Haemostasis in Haemorrhagic Fever With Renal Syndrome · not yet recruiting
- NCT07504926 — A Randomised Feasibility Study of CPAP in Large Airway Collapse · NA · not yet recruiting
- NCT07248423 — Start Taking Action for Tuberculosis in Kids · NA · not yet recruiting
- NCT07420881 — Start4All - Start Taking Action for TB Diagnosis (DARE-TB) · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06624631 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Liverpool School of Tropical Medicine
- Last refreshed: 21 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06624631.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing