Last reviewed · How we verify
NCT06621641
Nurse-led High-flow Nasal Cannula Weaning Protocol in Pediatric Intensive Care Unit
NA trial testing The new HFNC weaning protocol in Bronchiolitis in 150 participants. Completed in 30 June 2025.
30 May 2025
Quick facts
| Lead sponsor | Dr. Behcet Uz Children's Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 150 |
| Start date | 1 October 2024 |
| Primary completion | 30 May 2025 |
| Estimated completion | 30 June 2025 |
| Sites | 6 locations across Turkey (Türkiye) |
Drugs / interventions tested
- The new HFNC weaning protocol
Conditions studied
- Bronchiolitis — all drugs for Bronchiolitis →
- Respiratory Failure (Pediatric Patients) — all drugs for Respiratory Failure (Pediatric Patients) →
- High Flow Nasal Cannula — all drugs for High Flow Nasal Cannula →
Sponsor
Dr. Behcet Uz Children's Hospital
Who can join
Adults 1 Month to 24 Months, any sex, with Bronchiolitis or Respiratory Failure (Pediatric Patients). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Bronchiolitis is a leading cause of pediatric hospital admissions. Despite its limited clinical benefits, the use of HFNC in children with bronchiolitis is increasing. Previous studies using quality improvement (QI) methodologies have successfully reduced HFNC usage through weaning protocols and trials of standard oxygen therapy. This study involves implementing an HFNC initiation and weaning protocol at Aydın Maternity and Children's Hospital, involving infants aged 1-24 months admitted with bronchiolitis.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Impact of a nurse-driven high-flow nasal cannula weaning protocol on HFNC duration in infants with bronchiolitis: a randomized controlled trial.
Soydan E, Gökpınar EE, Sevinç ZG, Ceylan G, et al · · 2026 · PMID 41866402 · DOI 10.1007/s00431-026-06875-w
Verify or expand the search:
- PubMed search for NCT06621641
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Bronchiolitis
Currently open trials in the same condition.
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Other Dr. Behcet Uz Children's Hospital trials
Trials by the same sponsor.
- NCT06965400 — Comparison of Automatic and Manual Endotracheal Tube Cuff Pressure Monitoring in Pediatric Intensive Care Patients · NA · completed
- NCT06803355 — Comparison of Congenital Pneumonia and Transient Tachypnea of the Newborn · completed
- NCT06586411 — Comparison of Oxygenation Index and Oxygen Stretch Index · completed
- NCT07273487 — Nurse Education to Reduce Patient-Ventilator Asynchrony in the PICU · NA · completed
- NCT07252024 — Nurse-Led BIS-Guided Sedation Protocol in Pediatric Intensive Care · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06621641 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Dr. Behcet Uz Children's Hospital
- Last refreshed: 25 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06621641.
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