Who is sponsoring DEX-TBI?

DEX-TBI is sponsored by Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal.

What condition does DEX-TBI study?

DEX-TBI studies Traumatic Brain Injury, Agitation,Psychomotor.

What drugs are being tested in DEX-TBI?

Interventions: Dexmedetomidine, Placebo.

What is the status of DEX-TBI?

DEX-TBI is currently NOT_YET_RECRUITING.

Last reviewed 2024-10-01 · How we verify

Effects of Dexmedetomidine on Agitation in Critically Ill TBI Patients (DEX-TBI)

NCT06620393 PHASE2, PHASE3 NOT_YET_RECRUITING

Agitation is a frequent complication following traumatic braing injury in patients admitted to the intensive care unit. This agitation frequently results in the liberal use of rescue drugs such as antipsychotics, sedatives and opiates, which in turn may delay rehabilitation, liberation from mechanical ventilation and emergence from posttraumatic amnesia. Dexmedetomidine may be a better agent given it's light sedative properties. The main objective is to assess the feasibility of conducting a multicenter randomized controlled trial of dexmedetomidine following TBI in the ICU.

Details

Lead sponsor	Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Phase	PHASE2, PHASE3
Status	NOT_YET_RECRUITING
Enrolment	72
Start date	Tue Oct 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Tue Dec 01 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

Traumatic Brain Injury
Agitation,Psychomotor

Interventions

Dexmedetomidine
Placebo