NCT06619457 (SkinBioAge) is a NA clinical trial of Mitopure (Urolithin A) Cream in Skin Aging, sponsored by Amazentis SA.

Who is sponsoring NCT06619457?

NCT06619457 is sponsored by Amazentis SA.

What drugs are being tested in NCT06619457?

Interventions in NCT06619457: Mitopure (Urolithin A) Cream, Placebo Cream.

What condition does NCT06619457 study?

NCT06619457 studies Skin Aging.

Is NCT06619457 still recruiting?

NCT06619457 is currently completed. Last updated 3 April 2025.

Last reviewed 2025-04-03 · How we verify

NCT06619457: SkinBioAge

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Evaluation of the Anti-aging Efficacy of One Face Care Cosmetic Product

Completed NA Last updated 3 April 2025

What this trial tests

NA trial testing Mitopure (Urolithin A) Cream in Skin Aging in 36 participants. Completed in 12 December 2024.

Timeline

25 September 2024

Primary endpoint
12 December 2024

12 December 2024

Quick facts

Lead sponsor	Amazentis SA
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	basic science
Enrollment	36
Start date	25 September 2024
Primary completion	12 December 2024
Estimated completion	12 December 2024
Sites	1 location across Germany

Drugs / interventions tested

Mitopure (Urolithin A) Cream
Placebo Cream

Conditions studied

Skin Aging — all drugs for Skin Aging →

Sponsor

Amazentis SA — full company profile →

Who can join

Adults 50 to 75, any sex, with Skin Aging. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to evaluate the anti-wrinkle efficacy and effect on skin epigenetic and on mitochondrial morphology of a facial cosmetic product compared to a placebo

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Clinical Measurement of Transepidermal Water Loss.
Kundu D, Jayaraman A, Sen CK. · · 2026 · cited 4× · PMID 40476522 · DOI 10.1089/wound.2024.0148
The presence and induction of regioselective dehydroxylases dictate urolithin metabolism by Enterocloster species.
Pidgeon R, Giurleo A, Dridi L, Castagner B. · · 2025 · cited 1× · PMID 41298472 · DOI 10.1038/s41522-025-00849-w
Insights into the therapeutic strategies for aging and aging-associated diseases.
Dong R, Wu Q, Kan J, Fu C, et al · · 2026 · PMID 42225652 · DOI 10.1038/s41392-026-02662-z

Verify or expand the search:

Other recruiting trials for Skin Aging

Currently open trials in the same condition.

NCT07381218 — Focused Ultrasound Treatment for Facial Skin Laxity · NA · active not recruiting
NCT06900660 — Evaluation of the Skin-Beautifying Effects of Collagen Drinks · NA · active not recruiting
NCT06804772 — A Clinical Study to Evaluate the Efficacy of Activated Silk™ 27P-α in Subjects, Aged 35-65 Years of Age, to Improve the · NA · active not recruiting
NCT06816069 — Study on Safety and Efficacy of Monopolar Radio Frequency Device for Facial Skin Tightening · NA · active not recruiting
NCT06727292 — Biometrical Evaluation of the Efficacy of a Food Supplement Versus Placebo · NA · recruiting

Other Amazentis SA trials

Trials by the same sponsor.

NCT07517913 — Cerebrospinal Fluid Kinetics of Urolithin A · NA · not yet recruiting
NCT07517874 — Human Skin Safety Testing of 1 Mitopure Topical Products Using a Human Repeat Insult Patch Test (HRIPT) in Healthy Volun · NA · not yet recruiting
NCT07517887 — Anti-aging Efficacy Study on One Cosmetic Product Containing Mitopure · NA · not yet recruiting
NCT07517900 — Human Skin Safety Testing of 1 Mitopure Topical Product Using a Clinical Safety in Use Study in Healthy Volunteers · NA · not yet recruiting
NCT07231783 — The Effect of Urolithin A (Mitopure®) Supplementation on Muscle Strength in Healthy Middle-Aged Adults · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06619457 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Amazentis SA
Last refreshed: 3 April 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06619457.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing