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NCT06617507
The Effect of Selective Dorsal Rhizotomy Surgery on Walking in Children With Ambulatory Cerebral Palsy in Turkey
trial testing Group 1 in Cerebral Palsy Spastic Diplegia in 20 participants. Completed in 1 September 2024.
1 June 2024
Quick facts
| Lead sponsor | Acıbadem Atunizade Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 20 |
| Start date | 1 May 2024 |
| Primary completion | 1 June 2024 |
| Estimated completion | 1 September 2024 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Group 1
Conditions studied
- Cerebral Palsy Spastic Diplegia — all drugs for Cerebral Palsy Spastic Diplegia →
- Gait, Spastic — all drugs for Gait, Spastic →
Sponsor
Acıbadem Atunizade Hospital
Who can join
Adults 0 to 17, any sex, with Cerebral Palsy Spastic Diplegia or Gait, Spastic. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Cerebral Palsy (CP) is a motor disorder that develops during fetal brain development or due to non-progressive damage to the developing infant brain. These movement and posture disorders are classified as Spastic Type, Dyskinetic Type, Ataxic Type and Mixed Type (Rosenbaum, 2007). Spastic type CP accounts for 20% of all CP cases. Spastic type CP is divided into three groups: diparetic (38%), hemiparetic (39%) and quadriparetic (23%) (Novak et al., 2014). Lower extremity involvement is more common in diparetic cerebral palsy (DCP) (Donker et al., 2008). 98% of DCP cases vary between GMFS levels I and III. Walking rates are between 86-91% (Novak et al., 2014). Children with DCP can usually walk until the age of 4 (Cottalorda, 1998). However, these walks are often; Due to spasticity, muscle weakness, involuntary co-contraction, deficiencies in selective motor control, balance problems, structural changes of soft tissue and compensatory mechanisms (Manca, 2014), it can lead to musculoskeletal system problems and gait pathologies. Although the cerebral lesion that causes is static, children with spastic diplegia increase in height with age, and they may lose their ability to walk because bone length cannot be accompanied by muscle length at the same rate (Miller, 2020). Selective Dorsal Rhizotomy (SDR) surgery is an effective method for spasticity management in children with spastic DCP (Novak et al., 2014). The positive effect of SDR on function and mobility has been proven (Novak et al., 2020). It has been stated that SDR surgery applied to carefully selected candidates may be beneficial on gait quality in individuals with ambulatory CP (Chen, 2019). SDR surgery has been found to improve walking as a result of information collected from patients through a survey (Park, 2021). The aim of our study is to reveal the effect of SDR surgery performed in Turkey on gait function in children with CP using evaluation scales.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
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Related trials
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Trials testing the same drug.
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Other recruiting trials for Cerebral Palsy Spastic Diplegia
Currently open trials in the same condition.
- NCT07534228 — Comparative Effects of Play-Based Therapy and NDT in Diplegic CP · NA · active not recruiting
Other Acıbadem Atunizade Hospital trials
Trials by the same sponsor.
- NCT07407075 — MUSCLE STRENGTH IMBALANCE AND KINESIOPHOBIA IN MENISCUS PATIENTS · completed
- NCT06599281 — The Importance of Physiotherapy After Separation Surgery in Pygopagus Conjoined Twins · NA · not yet recruiting
- NCT06585397 — ICF-Based Evaluation of the Upper Extremity in Children With Quadriparetic Cerebral Palsy · completed
- NCT06610370 — Predicting Postoperative Ambulation Following Selective Dorsal Rhizotomy Based on Preoperative Gross Motor Function Scor · completed
- NCT06610357 — Evaluation of Long-Term Effects of Selective Dorsal Rhizotomy Surgery on Function and Mobility in Children With Cerebral · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06617507 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Acıbadem Atunizade Hospital
- Last refreshed: 27 September 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06617507.
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