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NCT06617130

The Efficacy of Amino Acid Supplementation in Treating Environmental Enteric Dysfunction Among Children At Risk of Malnutrition

Not yet recruiting NA Last updated 27 September 2024
What this trial tests

NA trial testing Corn soy bean blended flour porridge plus indispensable amino acid in Amino Acid, Stunting, Environmental Enteric Dysfunction in 66 participants. Not yet recruiting.

Timeline
1 November 2024
Primary endpoint
1 August 2026
1 December 2026

Quick facts

Lead sponsorKamuzu University of Health Sciences
PhaseNA
StatusNot yet recruiting
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingsingle
Primary purposeprevention
Enrollment66
Start date1 November 2024
Primary completion1 August 2026
Estimated completion1 December 2026
Sites1 location across Malawi

Drugs / interventions tested

Conditions studied

Sponsor

Kamuzu University of Health Sciences

Who can join

Adults 18 Months to 36 Months, any sex, with Amino Acid, Stunting, Environmental Enteric Dysfunction. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

A randomised controlled open label clinical trial to determine whether addition of indispensable amino acids (IAA) to standard complementary food will reduce occurrence of Environmental Enteric Dysfunction (EED) compared with provision of standard complementary food without IAA in healthy Malawian children aged 18-36 months with or without stunting.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Impact of indispensable amino acid supplementation on gut function in children at high risk of environmental enteropathy: protocol for an international coordinated group of randomised controlled trials.
    Lee GO, Owino V, Baquiran AFP, Pasanna RM, et al · · 2026 · PMID 42031499 · DOI 10.1136/bmjopen-2025-105456

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