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NCT06612177
Elderly Patients Surgical Site Infection Phenotypes Identification
trial in Postoperative Infection in 42,532 participants. Completed in 30 June 2024.
30 December 2023
Quick facts
| Lead sponsor | Weidong Mi |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 42,532 |
| Start date | 1 January 2023 |
| Primary completion | 30 December 2023 |
| Estimated completion | 30 June 2024 |
| Sites | 1 location across China |
Conditions studied
- Postoperative Infection — all drugs for Postoperative Infection →
- Geriatrics — all drugs for Geriatrics →
- Prediction — all drugs for Prediction →
- Surgical Site Infection — all drugs for Surgical Site Infection →
Sponsor
Weidong Mi
Who can join
65 and older, any sex, with Postoperative Infection or Geriatrics. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study utilizes Latent Class Analysis (LCA) to identify phenotypes of Surgical Site Infection (SSI) in elderly patients following non-cardiac surgery. By analyzing data from two large cohorts, the research establishes a predictive model that uncovers independent risk factors for SSI, including age, hyperlipidemia, and surgical characteristics. The model, with AUCs ranging from 0.753 to 0.791 across cohorts, offers a calibrated prediction of SSI risk. Furthermore, LCA delineates four distinct SSI subphenotypes, highlighting a critical subgroup with a higher infection rate. This subgroup presents a complex interplay of risk factors, indicating the need for tailored preventive strategies. The study's findings contribute to a nuanced understanding of SSI in elderly surgical patients and pave the way for more targeted infection control measures.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06612177
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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- Google Scholar
Related trials
Other recruiting trials for Postoperative Infection
Currently open trials in the same condition.
- NCT07228598 — Biofilm on Chest Drains After Thoracic Surgery: Clinical Impact and Antibiotic Resistance · recruiting
- NCT05052619 — Preventive Therapy of Postoperative Intra-abdominal Infection Based on Serum Lactate Changes · NA · recruiting
Other Weidong Mi trials
Trials by the same sponsor.
- NCT06547281 — Machine Learning Prediction of Multiple Infections in Elderly Surgical Patients · completed
- NCT06265493 — Postoperative Infectious Complications Calculator for Elderly Patients · completed
- NCT05742737 — Frailty Index as An Indicator Associated With Postoperative Adverse Outcomes In The Older Population · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06612177 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Weidong Mi
- Last refreshed: 9 October 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06612177.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing