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NCT06606262
Tonsillectomy Versus Tonsillotomy in the Treatment of Recurrent Acute Tonsillitis
NA trial testing Tonsillotomy in Tonsillitis Recurrent in 250 participants. Currently enrolling.
30 November 2026
Quick facts
| Lead sponsor | Tejs Ehlers Klug |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 250 |
| Start date | 31 October 2024 |
| Primary completion | 30 November 2026 |
| Estimated completion | 31 December 2029 |
| Sites | 2 locations across Denmark |
Drugs / interventions tested
- Tonsillotomy
- Tonsillectomy
Conditions studied
- Tonsillitis Recurrent — all drugs for Tonsillitis Recurrent →
Sponsor
Tejs Ehlers Klug — full company profile →
Who can join
15 and older, any sex, with Tonsillitis Recurrent. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Background: recurrent acute tonsillitis (RT) is a frequent condition affecting teenagers and adults. Patients suffer from recurring throat symptoms, fever and impaired quality of life (QOL). Tonsillectomy (TE) is the only well-known treatment, but studies indicate that tonsillotomy (TO) is associated with less morbidity (eg. pain and bleeding) and equal efficiency (e.g. reduced number of sore throat episodes and improved QOL). The investigator aim to clarify whether TO is a non-inferior alternative to TE. Methods: inclusion and randomization of 250 adult RT patients for TE or TO with a 12 month follow up. Comparisons will be made between groups, and outcome measures includes number of sore throat episodes, QOL and postoperative pain. Discussion: the study has the potential to improve the treatment of a prevalent disease by enhancing knowledge of an alternative procedure (TO) associated with less discomfort and risk than the current standard procedure (TE) and a presumably low risk of insufficiency.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06606262
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Related trials
Other trials of Tonsillotomy
Trials testing the same drug.
- NCT04657549 — Tonsil Surgery in Recurrent or Chronic Tonsillitis · NA · completed
- NCT03331497 — Tonsillotomy or Follow-up in PFAPA Syndrome · NA · completed
Other recruiting trials for Tonsillitis Recurrent
Currently open trials in the same condition.
- NCT07035314 — The Effect of Systemic Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Vs Intraoperative Infiltration of Steroids in Tonsi · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06606262 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Tejs Ehlers Klug
- Last refreshed: 19 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06606262.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing