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NCT06604286
Comparison of the Effects of Intraoral Postoperative Dexamethasone Applications After Mandibular Third Molar Surgery
Phase 4 trial testing In this group, patients received 8 mg IM dexamethasone injection into the masseter muscle after impacted tooth surgery. in Wisdom Teeth in 20 participants. Completed in 27 April 2024.
27 October 2023
Quick facts
| Lead sponsor | Afyonkarahisar Health Sciences University |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 28 April 2023 |
| Primary completion | 27 October 2023 |
| Estimated completion | 27 April 2024 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- In this group, patients received 8 mg IM dexamethasone injection into the masseter muscle after impacted tooth surgery.
- 8 mg IM dexamethasone injection into the pterygoid cavity after impacted tooth surgery. — full drug profile →
Conditions studied
- Wisdom Teeth — all drugs for Wisdom Teeth →
- Edema Face — all drugs for Edema Face →
- Trismus — all drugs for Trismus →
- Pain, Postoperative — all drugs for Pain, Postoperative →
Sponsor
Afyonkarahisar Health Sciences University
Who can join
Adults 18 to 25, any sex, with Wisdom Teeth or Edema Face. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study is to comparatively evaluate the effects of dexamethasone injected into the masseter muscle and pterygomandibular space after mandibular third molar surgery on postoperative pain, edema, trismus and quality of life. This clinical study will include 20 patients aged 18-25 years who underwent extraction of bilaterally impacted mandibular third molars in 2 consecutive sessions. The patients will randomly divide into two groups; Group 1 (n = 20) received 8 mg IM dexamethasone injection into the masseter muscle after the surgical procedure and Group 2 (n = 20) received 8 mg IM dexamethasone injection into the pterygomandibular space after the surgical procedure. Postoperative pain will record using the VAS scale at 6 hours, 12 hours, 24 hours, 2 and 7 days postoperatively. Edema, salivary cortisol and postoperative oral health quality of life and patient satisfaction will evaluate before surgery and on the 2nd and 7th days after surgery.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06604286
- Europe PMC full search
- ASCO Meeting Library
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- bioRxiv preprints
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06604286 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Afyonkarahisar Health Sciences University
- Last refreshed: 20 September 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06604286.
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