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NCT06601088: C-NMES-ATR
Achilles Tendon Rupture - Intervention With Electrical Stimulation
NA trial testing Neuromuscular Electrical Stimulation in Achilles Tendon Ruptures in 220 participants. Not yet recruiting.
15 February 2026
Quick facts
| Lead sponsor | Karolinska University Hospital |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 220 |
| Start date | 15 January 2025 |
| Primary completion | 15 February 2026 |
| Estimated completion | 30 December 2026 |
Drugs / interventions tested
- Neuromuscular Electrical Stimulation
Conditions studied
- Achilles Tendon Ruptures — all drugs for Achilles Tendon Ruptures →
- Immobilization — all drugs for Immobilization →
- Venous Thromboembolism (VTE) — all drugs for Venous Thromboembolism (VTE) →
- Muscle Atrophy — all drugs for Muscle Atrophy →
Sponsor
Karolinska University Hospital
Who can join
Adults 18 to 75, any sex, with Achilles Tendon Ruptures or Immobilization. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Acute Achilles tendon rupture (ATR) is an injury that is commonly associated with complications, such as blood clotting, muscle loss and tendon lengthening, all of which affect the long-term outcome and return to sports. These complication are related to the treatment of ATR with lower leg immobilization in a boot. The investigators aim to demonstrate that an intervention with calf neuromuscular electrical stimulation (C-NMES) during leg immobilization after ATR can 1) reduce blood clots, 2) lower the degree of muscle loss, 3) decrease tendon lengthening and 4) improve long-term outcome.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06601088
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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- Google Scholar
Related trials
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Trials testing the same drug.
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Other recruiting trials for Achilles Tendon Ruptures
Currently open trials in the same condition.
- NCT06639308 — Eendoscopic Versus Open Flexor Hallucis Longus Transfer in Managing Various Tendon Achilles Disorders · NA · active not recruiting
Other Karolinska University Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06601088 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Karolinska University Hospital
- Last refreshed: 19 September 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06601088.
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